Gender differences in patients undergoing TAVI: a multicentre study

Abstract

TAVI can be an effective and safe strategy in high surgical risk patients, regardless of the gender; life-threatening bleedings were reported more frequently in female patients, being the only independent predictor of death.

Effect of Gender After Transcatheter Aortic Valve Implantation: A Meta-Analysis

“…Four studies [8][9][10][11], for a total of 3,065 patients, reported the unadjusted rates of early outcomes by sex. Women experienced higher rates of major vascular complications (12.0% vs 7.4%) and of major and life-threatening bleeding (21.0% vs 13.0%), with lower rates of moderate to severe aortic regurgitation (3.1% vs 5.4%).…”

“…In this setting, the effect of gender may be relevant to understand timing and opportunity of percutaneous intervention, but only a limited number of studies, reporting variable results, have investigated genderspecific differences in outcome after TAVI [9][10][11][12][13][14][15][16][17]. A recent meta-analysis on the same topic reported better short-term and midterm survival for women.…”

Transcatheter Aortic Valve Replacement for Severe Aortic Stenosis

“…21,22 The PARTNER trial also suggested that TAVR was associated with lower mortality than SAVR among women. [23][24][25] [23][24][25] …”

Outcomes in patients undergoing transcatheter aortic valve replacement: a sex-based story of success?

“…Available data suggests that female patients are at higher risk of bleeding and vascular complications (4,5) resulting in increased rehospitalization and mortality rates as compared to male subjects (6,7). In contrast, other studies report on either improved female or gender neutral survival rates after TAVR (8)(9)(10)(11).…”