Gender differences in risk-taking behaviour in youth with epilepsy: a Norwegian population-based study

Alfstad, Kristin Å.; Clench‐Aas, Jocelyne; Roy, Betty Van; Mowinckel, Petter; Gjerstad, Leif; Lossius, Morten I.

doi:10.1111/j.1600-0404.2011.01537.x

Cited by 15 publications

(14 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Epilepsy and schizophrenia have similar neuroanatomical findings and a common genetic susceptibility, and rates in the current study are commensurate with previous studies . In a Norwegian study of adolescents, 8.3% reported daily alcohol consumption and 12.4% reported illicit substance use . The current study found alcohol misuse in 7.0% and drug misuse in 13.9% of adolescents with epilepsy.…”

Section: Discussionsupporting

confidence: 89%

“…24 In a Norwegian study of adolescents, 8.3% reported daily alcohol consumption and 12.4% reported illicit substance use. 25 The current study found alcohol misuse in 7.0% and drug misuse in 13.9% of adolescents with epilepsy. We were not able to locate a study investigating personality disorders in children and adolescents with epilepsy with which to compare our rates of personality disorders.…”

Section: Discussionmentioning

confidence: 46%

See 1 more Smart Citation

Neurodevelopmental and mental health comorbidities in children and adolescents with epilepsy and migraine: a response to identified research gaps

Wagner

Wilson

Smith

et al. 2014

Develop Med Child Neuro

View full text Add to dashboard Cite

Aim To determine the distribution and risk characteristics of comorbid neurodevelopmental and mental health comorbidities among children and adolescents (6–18y) with epilepsy or migraine (i.e. a neurological condition with shared features and potential etiology) compared with lower extremity fracture (LEF). Method This case–control study involved a subset analysis of surveillance data in South Carolina, USA. Hospital admission, outpatient, and emergency department visits for individuals with an International Classification of Disease, 9th revision Clinical Modification diagnosis of epilepsy (n=6730; 54.5% females, 45.5% males; mean age [SD] 14y 2mo [4y 5mo]); migraine (n=10 495; 74.5% females, 25.5% males; 15y 6mo [2y 6mo]), or LEF (n=15 305; 40.3% females, 59.7% males; 13y 11mo [2y 11mo]) from January 1 2000 to December 31 2011 were identified. The association of epilepsy, migraine, or LEF with any mental health comorbidity was evaluated with univariate and multivariate polytomous logistic regression. Results Comorbidities were highly prevalent in children and adolescents, with epilepsy with a rate of 29.7% (95% confidence interval [CI]: 28.6–30.8) for mental health comorbidities and 30.8% (95% CI: 29.7–31.9) for neurodevelopmental comorbidities. The odds of mental health comorbidity was 2.20 (95% CI: 2.02–2.39) for children and adolescents with epilepsy and 1.60 (95% CI: 1.48–1.73) for migraine, in reference to children and adolescents with LEF after adjusting for potential confounders. Prevalence and risk for specific comorbidities are presented. Interpretation Neuropathophysiological and psychosocial factors specific to epilepsy may provide more risk for adolescents with epilepsy compared to migraine.

show abstract

Section: Discussionsupporting

confidence: 89%

Section: Discussionmentioning

confidence: 46%

Neurodevelopmental and mental health comorbidities in children and adolescents with epilepsy and migraine: a response to identified research gaps

Wagner

Wilson

Smith

et al. 2014

Develop Med Child Neuro

View full text Add to dashboard Cite

show abstract

“…Males with epilepsy are known to demonstrate more risk-taking behavior when compared to their male controls without epilepsy, 42 whereas females are thought to have more injuries sustained at home. Variables that may influence the risk for injury include gender, age, socioeconomic status, and epilepsy duration.…”

Section: Summary Of Findingsmentioning

confidence: 99%

Risk factors for injury in a community‐treated cohort of patients with epilepsy in Australia

et al. 2019

View full text Add to dashboard Cite

Summary Objective There remains a paucity of knowledge regarding specific epilepsy‐related risk factors for accidents and injuries in people with epilepsy. Injury studies in people with epilepsy are overrepresented, with tertiary based populations that are prone to bias from severe disease. This study aims to assess the contribution of epilepsy‐related risk factors to injuries in a community‐based cohort. Methods We performed a retrospective nested case‐control study on patients recruited into the Tasmanian Epilepsy Register (TER) from July 1, 2001 to June 30, 2002. The TER is a community‐based cohort of patients with epilepsy in Tasmania, Australia, recruited from the national prescription database and interviewed for epilepsy diagnosis, injuries, and risk factors using validated questionnaires with diagnosis made by an epilepsy specialist. The primary outcome measures were lifetime and recent 12‐month injury. Multivariate logistic regression with multiple imputation modeling responder nondisclosure was performed, adjusting for age, gender, region, socioeconomic status, seizure frequency, and epilepsy duration. Results A total of 819 patients with epilepsy were included in this study. Ten percent of patients experienced an injury in the preceding year. Before adjusting for seizure frequency, any seizure over the past 12 months was associated with recent injury (adjusted odds ratio [OR] = 7.90, 95% confidence interval [CI] = 4.17‐14.96). Impaired awareness, cluster seizures, sleep‐only seizures, and convulsive seizure were characteristics found to significantly influence injuries irrespective of seizure frequency. Although a warning appeared initially protective for recent injuries (OR = 0.39, 95% CI = 0.22‐0.69), this was entirely explained by seizure frequency, with the effect becoming nonsignificant. Significance Likely due to their unpredictable nature, seizures expose patients with epilepsy to a high risk of life‐threatening injury. These findings emphasize the importance of seizure freedom for maximizing the safety of patients with epilepsy.

show abstract

“…A Norwegian population-based questionnaire study of 19,995 adolescents (age range 13-19 years), of whom 247 had a history of epilepsy, looked at risk-taking behavior. 6 Such behavior was reported more often in the epilepsy group with 8.3% (1.0% in controls; p < 0.001) reporting daily alcohol consumption, 12.4% (5.5% of controls; p < 0.001) having tried illegal substances, and 19.7% (8.5% in controls; p < 0.001) having committed criminal offenses (fight with weapon, burglary, or threats to obtain money). The risktaking behavior, however, was gender dependent; girls with epilepsy were similar to the control group.…”

Section: Comorbiditymentioning

confidence: 99%

Transition: Driving and exercise

et al. 2014

View full text Add to dashboard Cite

show abstract

Gender differences in risk-taking behaviour in youth with epilepsy: a Norwegian population-based study

Cited by 15 publications

References 24 publications

Neurodevelopmental and mental health comorbidities in children and adolescents with epilepsy and migraine: a response to identified research gaps

Neurodevelopmental and mental health comorbidities in children and adolescents with epilepsy and migraine: a response to identified research gaps

Risk factors for injury in a community‐treated cohort of patients with epilepsy in Australia

Transition: Driving and exercise

Contact Info

Product

Resources

About