Gender Differences in the Diagnosis of Dyslipidemia: ESCARVAL-GENERO

Soriano-Maldonado, Cristina; López-Pineda, Adriana; Orozco-Beltrán, Domingo; Quesada, José A.; Jl, Alfonso Sánchez; Pallarés‐Carratalá, Vicente; Navarro-Pérez, Jorge; Gil-Guillén, Vicente; Martín-Moreno, José M.; Carratalá‐Munuera, Concepción

doi:10.3390/ijerph182312419

Cited by 20 publications

(16 citation statements)

References 43 publications

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“…Our findings are consistent with the findings reported by Soriano-Maldonado et al who provided researchbased evidence that dyslipidemia is heterogeneous based on gender and it differs significantly between males and females in terms of prevalence and risks [23].…”

Section: Discussionsupporting

confidence: 93%

“…Another cross-sectional study conducted on 275 volunteered diabetic patients showed significant increase in all examined lipid parameters (TC, TG, LDL-C) and calculated indexes (lipid accumulation product, visceral adiposity index) across HBA1c three groups, with exception of HDL-C that decreased along with increment in HBA1c, TC (OR = 1.46, 95% CI (1.18-1.81), P = 0.001), TG (OR = 1.44, 95% CI (1.18-1.76), P < 0.001), and LDL-C (OR = 1.42, 95% CI (1.11-1.83), P = 0.006), increased by 1 mmol/L each, probabilities of higher HBA1c increased by 46%, 44% and 42%, respectively [ 23 ]. High TC and TG were the independent predictors of higher HBA1c.…”

Section: Discussionmentioning

confidence: 99%

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Prevalence and Regulation of Dyslipidemia Among Adults With Type 2 Diabetes From Three Primary Health Care Centers in Riyadh

Saleh¹,

Alharbi²,

Alanazi³

et al. 2022

Cureus

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Background Dyslipidemia is an added risk factor in patients with type 2 diabetes who are more prone to develop cardiovascular diseases as it implies an alteration of the lipid level leading to serious health complications. Objective This study aimed at assessing the prevalence of dyslipidemia among patients with type 2 diabetes and comparing the lipid profile measurements between controlled and uncontrolled type 2 diabetic patients. Method A cross-sectional retrospective study was performed in three primary health care centers in Saudi Arabia. A sample of 418 patients with type 2 diabetes was enrolled in this study. To collect data, the researcher used a structured questionnaire and retrieved patients' data from the electronic medical records in the study setting. Results The findings of the study showed that 82.1% of type 2 diabetes mellitus (DM) patients recruited in this study were dyslipidemic. In addition, it was found that there was a significant difference in triglycerides, fasting blood sugar (FBS), and high-density lipoprotein (HDL) between controlled and uncontrolled diabetic patients (p≤0.05). Moreover, a significant interaction was found between gender, HbA1c control, educational level, and frequency of exercising on one hand and dyslipidemia on the other hand (p≤0.05). Conclusion The study concluded that there is a high prevalence of dyslipidemia among type 2 diabetic patients in Saudi Arabia and a significant interaction between dyslipidemia and diabetic patients' gender, HbA1c control, educational level, and frequency of exercising. The study recommends increasing type 2 diabetic patients' awareness regarding the management of diabetes and dyslipidemia and the importance of providing educational intervention regarding diabetes self-care activities.

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Section: Discussionsupporting

confidence: 93%

Section: Discussionmentioning

confidence: 99%

Prevalence and Regulation of Dyslipidemia Among Adults With Type 2 Diabetes From Three Primary Health Care Centers in Riyadh

Saleh¹,

Alharbi²,

Alanazi³

et al. 2022

Cureus

View full text Add to dashboard Cite

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“…Furthermore, our study is consistent with prior studies suggesting associations between covariates and dyslipidemia, such as gender [ 79 ], urban–rural difference [ 77 ], marital status [ 80 ], age [ 29 ], years of education [ 81 ], smoking status [ 82 ], and alcohol use [ 83 , 84 ].…”

Section: Discussionsupporting

confidence: 91%

The Effect of Psychological Burden on Dyslipidemia Moderated by Greenness: A Nationwide Study from China

Liu

et al. 2022

IJERPH

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Globally, dyslipidemia is now become a leading risk factor for many adverse health outcomes, especially in the middle-aged and elderly. Recent evidence suggests that exposure to greenness and the relief of a psychological burden may decrease the prevalence of dyslipidemia. The objective of our study was to examine whether a green space can moderate the association between mental health status and dyslipidemia. Our study selected the datasets of depression symptoms, dyslipidemia from the China Health and Retirement Longitudinal Study (CHARLS), and the satellite-based normalized difference vegetation index (NDVI) from the 30 m annual maximum NDVI dataset in China in 2018. Ultimately, a total of 10,022 middle-aged and elderly Chinese were involved in our study. Multilevel logistic regressions were performed to examine the association between symptoms of depression and dyslipidemia, as well as the moderate effect of greenness exposure on the association. Our research suggested that adults diagnosed with depression symptoms were more likely to suffer from dyslipidemia. In addition, the NDVI was shown to moderate the effect of depression on dyslipidemia significantly, though the effect was attenuated as depression increased. Regarding the moderate effect of the NDVI on the above association across age, gender, and residence, the findings presented that females, the elderly, and respondents living in urban areas were at a greater risk of having dyslipidemia, although the protective effect of the NDVI was considered. Likewise, the moderate effect of the NDVI gradually decreased as the level of depression increased in different groups. The current study conducted in China provides insights into the association between mental health, green space, and dyslipidemia. Hence, improving mental health and green spaces can be potential targets for medical interventions to decrease the prevalence of dyslipidemia.

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“…In addition, many clinical variables not recorded in the EHR were detected. In a previous study of the same cohort but a dyslipidemic population, 18% of adults met the diagnostic criteria for dyslipidemia and had no recorded diagnosis or treatment prescribed (DI), with DI greater in women, young age, normal weight, no smoking habit, and those with alterations in SBP, HDL cholesterol, total cholesterol, LDL cholesterol, or triglycerides, or missing values in their EHR ( 28 ). A similar pattern exists between both sexes, and in DI in both hypertension and dyslipidemia, there is a lack of assessment of subclinical disease (comorbidities).…”

Section: Discussionmentioning

confidence: 99%

“…had no recorded diagnosis or treatment prescribed (DI), with DI greater in women, young age, normal weight, no smoking habit, and those with alterations in SBP, HDL cholesterol, total cholesterol, LDL cholesterol, or triglycerides, or missing values in their EHR (28). A similar pattern exists between both sexes, and in DI in both hypertension and dyslipidemia, there is a lack of assessment of subclinical disease (comorbidities).…”

Section: Discussionmentioning

confidence: 99%

Characterizing Diagnostic Inertia in Arterial Hypertension With a Gender Perspective in Primary Care

Pallarés‐Carratalá

Carratalá‐Munuera²,

López-Pineda³

et al. 2022

Front. Cardiovasc. Med.

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Background and ObjectivesSubstantial evidence shows that diagnostic inertia leads to failure to achieve screening and diagnosis objectives for arterial hypertension (AHT). In addition, different studies suggest that the results may differ between men and women. This study aimed to evaluate the differences in diagnostic inertia in women and men attending public primary care centers, to identify potential gender biases in the clinical management of AHT.Study Design/Materials and MethodsCross-sectional descriptive and analytical estimates were obtained nested on an epidemiological ambispective cohort study of patients aged ≥30 years who attended public primary care centers in a Spanish region in the period 2008–2012, belonging to the ESCARVAL-RISK cohort. We applied a consistent operational definition of diagnostic inertia to a registry- reflected population group of 44,221 patients with diagnosed hypertension or meeting the criteria for diagnosis (51.2% women), with a mean age of 63.4 years (62.4 years in men and 64.4 years in women).ResultsOf the total population, 95.5% had a diagnosis of hypertension registered in their electronic health record. Another 1,968 patients met the inclusion criteria for diagnostic inertia of hypertension, representing 4.5% of the total population (5% of men and 3.9% of women). The factors significantly associated with inertia were younger age, normal body mass index, elevated total cholesterol, coexistence of diabetes and dyslipidemia, and treatment with oral antidiabetic drugs. Lower inertia was associated with age over 50 years, higher body mass index, normal total cholesterol, no diabetes or dyslipidemia, and treatment with lipid-lowering, antiplatelet, and anticoagulant drugs. The only gender difference in the association of factors with diagnostic inertia was found in waist circumference.ConclusionIn the ESCARVAL-RISK study population presenting registered AHT or meeting the functional diagnostic criteria for AHT, diagnostic inertia appears to be greater in men than in women.

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Gender Differences in the Diagnosis of Dyslipidemia: ESCARVAL-GENERO

Cited by 20 publications

References 43 publications

Prevalence and Regulation of Dyslipidemia Among Adults With Type 2 Diabetes From Three Primary Health Care Centers in Riyadh

Prevalence and Regulation of Dyslipidemia Among Adults With Type 2 Diabetes From Three Primary Health Care Centers in Riyadh

The Effect of Psychological Burden on Dyslipidemia Moderated by Greenness: A Nationwide Study from China

Characterizing Diagnostic Inertia in Arterial Hypertension With a Gender Perspective in Primary Care

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