Gender-related differences in patients with acute heart failure: Management and predictors of in-hospital mortality

Gender-related differences in clinical profile and outcome of patients with heart failure. Results of the RICA Registry

“…Levy et al 20 observed that the risk of developing HF in patients with hypertension compared with patients with normal blood pressure was almost 2 fold in men and 3 fold in women, adjusting for age and other factors. In fact, the etiology of HF in women is predominantly hypertensive and valvular, as has been mentioned previously, 5 while the ischemic etiology predominates in men, 3,4,10,11,19 findings that were also observed in our study. Moreover, in our study, obesity was more common in the women, as has been reported in the literature, 10,19 although not unanimously.…”

“…As has been reported in the literature, women have a lower prevalence of ischemic heart disease and COPD 2---4,10,11,19 and a higher frequency of hypertension. There is almost unanimous agreement in the various series on the higher prevalence of hypertension in women, 3,4,9---12,19 with higher systolic blood pressure readings, 3,4,9,10,12,19 as was observed in our study. A greater risk of developing HF has been observed with arterial hypertension in women than in men.…”

Precipitating factors of heart failure admission: Differences related to age and left ventricular ejection fraction

“…Moreover, the identification of predictors of readmission in especially vulnerable population subgroups, such as the elderly, may provide useful insight for clinicians in designing prevention strategies. Although some studies have explored the factors leading to decompensation, they have mostly been conducted with younger patients [4][5][6][7][8] or mainly in systolic disfunction [7,[9][10]. Therefore, information is lacking in relation to PF in very elderly and preserved LVEF HF patients, the group with the highest number of readmissions.…”

Incidencia y letalidad intrahospitalaria por insuficiencia cardiaca en Chile: ¿Existen diferencias por sexo?

“…Similarmente, Hsich et al mostraron que mujeres y hombres con fracción de eyección del ventrículo izquierdo reducida o preservada tienen similar letalidad intrahospitalaria 21 . Resultados similares se encuentran en el estudio de Parissis et al, concluyendo que la mortalidad intrahospitalaria por IC en hombres y mujeres no difiere significativamente (10,5% y 11% respectivamente) 12 .…”

“…Las mujeres con diagnóstico de IC son de mayor edad, con fracción de eyección preservada, mayor número de comorbilidades, mayor limitación funcional y peor calidad de vida que los hombres 9,10 . Pese a estas diferencias, en la mayoría de los estudios, el sexo no se asocia con mayor mortalidad intrahospitalaria [11][12][13][14][15] . En Chile, los datos de morbimortalidad asociada a IC son prácticamente inexistentes.…”