Background:
The pattern of head-and-neck cancer (HNC) differs across India due to considerable differences in regional customs, tobacco consumption behaviors, socio-economic status, and other regional risk-factors.
Objectives:
The primary objective of this study was to assess the epidemiological and demographic profile of patients with HNC from Bihar, India. The secondary objective was to evaluate differences in the incidence of HNC across different anatomical sites with respect to tobacco use, gender, and geographical location.
Materials and Methods:
We conducted a retrospective analysis of 3230 newly diagnosed, biopsy-proven HNC cases from Bihar, treated at the Department of Head-and-Neck Cancer, Mahavir Cancer Institute and Research Center, Patna, between January 2021 and December 2022. Data on age, gender, address, tobacco habit, site of disease, and other details were extracted from clinical records for statistical analysis.
Results:
This hospital-based study showed a predominance of male patients, with a male-to-female ratio of 5.37:1. The majority of patients were aged between 41-60 years, with significant gender disparities noted across all the age groups (P < 0.05). The oral cavity was identified as the most common site of HNC, accounting for 71.6% in males (n = 1949/2723) and 50.5% in females (n = 256/507). Within the oral cavity, the buccal mucosa and tongue were the most prevalent subsites. The number of patients from North Bihar was more in comparison to South Bihar. The most common tobacco habits were khaini and betel quid, both widely cultivated in Bihar.
Conclusion:
This study highlights a high prevalence of non-smoking tobacco consumption among the patients with HNC in Bihar. The oral cavity, particularly the buccal mucosa, was found to be the most affected site. Variations in the pattern of HNC were noted with respect to tobacco use, gender, and geographical location.