“…However, within the high GjC group of Gram-positive bacteria, Mycobacterium tuberculosis and S. coelicolor A3(2) each have more than five eukaryotic-type protein kinases. Mycobacterium leprae is also reported to have more than three kinases (Fsihi et al, 1996) ; Chlamydia trachomatis has two (Pkn5 and PknD), whereas spirochaetes (Borrelia burg- PkaB 0n82972 PkaG 1n39321 1n60986 AfsK 1n38722 1n66052 0n72440 PkaE 1n23367 1n24283 1n31829 1n45375 PkaF 1n21327 1n30989 1n44339 1n56899 1n19901 PkaD 1n43179 1n56128 1n51208 1n60317 1n53002 1n46337 Pks3 1n43914 1n51712 1n83070 1n73382 1n39806 1n54905 1n4363 1998 (Cole et al, 1998). On the other hand, HPO432, SLL0776 and PHCJ009 gave high scores for homology with several kinases : HPO432 with PknK, CTPknD and PH009 ; SLL0776 with PkaD, AfsK, PknE, CTPknD, SLR1225, SLR1443, SLR1697 and SLR0152 ; and PHCJ009 with PkaE, YloP, PknH, PknL, CTPkn5 and CTPknD (Table 3).…”