Gene frequencies and admixture estimates in the state of Puebla, Mexico

Abstract

Three hundred ninety-three individuals from the Universidad Autónoma de Puebla and its University Hospital were studied to determine the distribution of ABO, MN, Rh-Hr, Duffy, and Diego blood groups; red cell hemoglobin and glucose-6-phosphate dehydrogenase variants; and serum haptoglobins, albumins, and factor Bf types. With the results we estimated that the proportions of black, indian, and white genes are 10.7%, 56.3%, and 33.0%, respectively, in a trihybrid model. Reasons are given as to why the black ancestry may be artifically high, and it is pointed out that independent confirmation with other markers is needed before the figure can be accepted as a true value.

JAG1 and COL1A1 polymorphisms and haplotypes in relation to bone mineral density variations in postmenopausal Mexican-Mestizo Women

“…On the other hand, differences in allelic frequencies were reported by Kung et al (2010) in different ethnic groups. The findings observed in the study by Kung et al (2010) may be due to genetic background because the Mexican-Mestizo population is comprised of a mixture of Europeans and Africans with native indigenous individuals (Lisker et al 1990). …”

Ancestry informative markers and admixture proportions in northeastern Mexico

“…6,11,21,23,[25][26][27][28][29][30] The admixture estimates reported in these studies are based on blood groups, serum proteins, STRs and AIMs. As a whole, the data are consistent with the Mexican population history and reflect a gradient with a higher proportion of Native American ancestry in the southern states and increased ancestry of the African contribution in the states of the Gulf of Mexico.…”

LMP2 and LMP7 gene polymorphism in Mexican populations: Mestizos and Amerindians

“…Results from these studies have shown a proportion of 56% of Amerindian genes, 40% of Caucasian genes and 4% of black genes in this population. [13][14][15] Genetic distances calculated from LMP allele frequencies show that Mexican Mestizos are related to Spaniards and Mexican Amerindians. These data corroborate the previously admixture results reported using other genetic markers and confirm the presence of Spaniard genes (who came to America during the 16th century) in the Mexican Mestizo population.…”

“…Results from these studies have shown a proportion of 56% Amerindian genes, 40% Caucasian genes, and 4% black genes. [13][14][15] The aim of the present work was to study the LMP allele and genotype distribution in Mexican populations and establish the admixture between them and other populations using this polymorphism.…”