2004
DOI: 10.1016/j.ijoa.2004.01.005
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General anaesthesia with target controlled infusion of propofol for planned caesarean section: maternal and neonatal effects of a remifentanil-based technique

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Cited by 88 publications
(65 citation statements)
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“…Remifentanil is metabolized by nonspecific tissue and plasma esterases and is therefore eliminated independently of hepatic function. Restoration from remifentanil does not relate to dose and infusion time so it can be used as induction and anesthesia maintenance; however, it may lead to decreased Apgar scores and mild respiratory depression, and the need for transient mask ventilation has been reported in 6 of 10 neonates [37]. Remifentanil was not used in any of these cases.…”
Section: Discussionmentioning
confidence: 99%
“…Remifentanil is metabolized by nonspecific tissue and plasma esterases and is therefore eliminated independently of hepatic function. Restoration from remifentanil does not relate to dose and infusion time so it can be used as induction and anesthesia maintenance; however, it may lead to decreased Apgar scores and mild respiratory depression, and the need for transient mask ventilation has been reported in 6 of 10 neonates [37]. Remifentanil was not used in any of these cases.…”
Section: Discussionmentioning
confidence: 99%
“…In clinical practice, however, propofol appears acceptable. [11] Propofol however may better attenuate the hemodynamic response to laryngoscopy and intubation. [12] Apart from the teratogenic effects, many drugs are responsible for premature labour, abortion and growth retardation.…”
Section: Discussionmentioning
confidence: 99%
“…However, the neonatal respiratory depression was apparently transient. Spontaneous respiration was established rapidly by mask ventilation or naloxone [5,6,16,17].…”
Section: Discussionmentioning
confidence: 99%
“…The safety of remifentanil in neonatal outcomes has been investigated in several prospective studies to J Anesth (2012) 26:275-279 277 determine the optimal technique for cesarean section under general anesthesia [5,6,18]. van de Velde et al [6] evaluated the maternal and neonatal effects of a propofol/ remifentanil-based anesthesia technique in 10 patients undergoing cesarean section under general anesthesia.…”
Section: Discussionmentioning
confidence: 99%
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