General approach of Systematic Toxicological Analysis — Current status and future

Novel drugs of abuse and bioanalytical strategies in Forensic Toxicology: metabolomics, analysis in blood, urine or DBS and human performance and post mortem cases

“…In this context, the main goal is to analyze a sample in order to provide the identification and quantification of compounds of interest, followed by the interpretation of the results in the context of the case (TIAFT, 2001). Systematic Toxicological Analysis (STA) is the tool used for general forensic toxicological analysis, by using a well-planned analytical approach to identify compounds with potential toxicity and their metabolites in biological fluids (MUELLER et al 1994;DE ZEEUW, 1997;TIAFT, 2001). STA can be a complex and challenging investigation, based on the case history, available biological samples, required extraction and analytical technique and the available database (JOYE et al, 2019).…”