GENERAL CARDIOLOGY: Cardiac tumours: diagnosis and management

Shapiro, Leonard M.

doi:10.1136/heart.85.2.218

Cited by 289 publications

(313 citation statements)

References 11 publications

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“…Primary cardiac tumours are rare (0.02-0.19%) [2][3][4]; myxoma is the commonest benign tumour in adults (45-50%) [5]. Myxomas present between the ages of 30 -70 years, and occur more frequently in women [5,6].…”

Section: Discussionmentioning

confidence: 99%

“…The majority of myxomas (75-90%) originate in the LA from the fossa ovalis [5][6][7]. Clinical features include dyspnoea, syncope, arrhythmias, oedema, haemoptysis, and sudden death [2]. Systemic features of embolic phenomena (30-40%) [8] can result in pulmonary embolism, stroke and vasculitis and can mimic infective endocarditis [5][6][7][8].…”

Section: Discussionmentioning

confidence: 99%

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Left Atrial Myxoma With Concurrent Saddle Pulmonary Embolism and Duke’s B Colorectal Adenocarcinoma

Mehra

2013

J Med Cases

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A 64-year-old male with previous Duke's B adenocarcinoma of the colon, successfully treated with surgery and chemotherapy presented several months later with dyspnoea and atrial fibrillation. Investigations showed that he had a left atrial myxoma and a concurrent saddle pulmonary embolus. Full anticoagulation with unfractioned heparin was administered followed by surgical resection of the myxoma. Links between pulmonary emboli and underlying carcinoma are well established. However, to our knowledge, this is only the second case in the English literature where a patient has had both an adenocarcinoma of the colon and a myxoma. There are no links between a pulmonary saddle embolism and left atrial myxoma or between a right sided myxoma and a pulmonary saddle embolus and where the embolism is not a fragment of the myxoma.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Left Atrial Myxoma With Concurrent Saddle Pulmonary Embolism and Duke’s B Colorectal Adenocarcinoma

Mehra

2013

J Med Cases

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“…Diagnosis of cardiac myxoma depends on a high index of suspicion and can almost be made by echocardiography; 11) 90% originate from the LA 11)12) and the echocardiographic appearance is heterogenous with small lucencies. 11) Two different morphologic types of myxomas have been determined by means of echocardiography: 1) the round type, which is solid and smooth with a non-mobile surface; and 2) the polypoid type, which is soft and irregular in shape with a mobile surface.…”

Section: )10)mentioning

confidence: 99%

“…11) Two different morphologic types of myxomas have been determined by means of echocardiography: 1) the round type, which is solid and smooth with a non-mobile surface; and 2) the polypoid type, which is soft and irregular in shape with a mobile surface. 13) Ha and coworkers 14) showed that prolapsing and polypoid tumors were associated with a higher incidence of embolism.…”

Section: )10)mentioning

confidence: 99%

Probable Left Atrial Myxoma Presenting as Concurrent Cerebral and Myocardial Infarctions

et al. 2008

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Concurrent cerebral and coronary artery embolization is a theoretically possible, but extremely rare complication of an atrial myxoma. We present a paitent with a left atrial mass (a probable myxoma) who presented with concurrent cerebral and myocardial infarctions due to emboli of tumor origin. An 84-year-old woman presented with an acute cerebral infarction of the middle cerebral artery territory. Several hours after admission, she complained of chest pain consistent with a myocardial infarction. Transthoracic and transesophageal echocardiographic studies revealed the presence of a large, mobile, heteroechoic mass with a few daughter nodules in the left atrium, compatible with a myxoma. Coronary angiography disclosed subtotal occlusion of the ramus intermedius branch and visible tumor vascularization adjacent to the right coronary artery. With medical treatment, including anticoagulation, the patient was stabilized and had an uneventful clinical course for the ensuing 6 months since discharge.

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“…Dear Sirs, Myxomas comprise the majority of cardiac tumors [1]. Patients may experience signs of cardiac obstruction or systemic embolism, accompanied by non-specific systemic symptoms such as fever or malaise, [2].…”

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confidence: 99%

Etoposide/carboplatin chemotherapy for the treatment of metastatic myxomatous cerebral aneurysms

et al. 2014

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GENERAL CARDIOLOGY: Cardiac tumours: diagnosis and management

Cited by 289 publications

References 11 publications

Left Atrial Myxoma With Concurrent Saddle Pulmonary Embolism and Duke’s B Colorectal Adenocarcinoma

Left Atrial Myxoma With Concurrent Saddle Pulmonary Embolism and Duke’s B Colorectal Adenocarcinoma

Probable Left Atrial Myxoma Presenting as Concurrent Cerebral and Myocardial Infarctions

Etoposide/carboplatin chemotherapy for the treatment of metastatic myxomatous cerebral aneurysms

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