We provide a general and tractable framework under which all multiple yield curve modeling approaches based on affine processes, be it short rate, Libor market, or HJM modeling, can be consolidated. We model a numéraire process and multiplicative spreads between Libor rates and simply compounded OIS rates as functions of an underlying affine process. Besides allowing for ordered spreads and an exact fit to the initially observed term structures, this general framework leads to tractable valuation formulas for caplets and swaptions and embeds all existing multi-curve affine models. The proposed approach also gives rise to new developments, such as a short rate type model driven by a Wishart process, for which we derive a closed-form pricing formula for caplets. The empirical performance of two specifications of our framework is illustrated by calibration to market data.2010 Mathematics Subject Classification. 91G30, 91B24, 91B70. JEL Classification E43, G12. Key words and phrases. Multiple yield curves, Libor rate, forward rate agreement, multiplicative spread, affine processes. Acknowledgements. The authors are grateful to two anonymous referees for their valuable comments that helped to significantly improve the paper. 1 Similarly as in [5,28], we denote by Xibor a generic interbank offered rate for unsecured term lending, such as the Libor rate in the London interbank market and the Euribor rate in the Eurozone. While the theoretical framework developed in the present paper applies to generic Xibor rates, the empirical results reported in Section 6 refer to Euribor rates. 1 arXiv:1603.00527v2 [q-fin.MF]