General Hospitalization and Intensive Care Unit-Related Factors of COVID-19 Patients in Northeastern Colombia: Baseline Characteristics of a Cohort Study

Cáceres Ramírez, Catalina; Lora Mantilla, Alvaro José; Parra Gómez, Laura Alejandra; Ortegón Vargas, Valentina; Posso Paz, Mariam; Flórez Esparza, Valeria; Gómez Lahitton, Edgar; Villabona Flórez, Silvia Juliana; Rocha Lezama, Maria Catalina; Camacho López, Paul Anthony

doi:10.7759/cureus.43888

Cited by 3 publications

References 40 publications

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Association Between Chest Imaging and Persistent Symptoms: A Six-Month Follow-Up Study on COVID-19 SurvivorsChest imaging and COVID-19 persistent symptoms at six months follow-up.

Mantilla,

Ramirez,

Gutierrez

et al. 2024

Preprint

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Background: The COVID-19 pandemic remains a global challenge with over 750 million cases. Post-COVID-19 condition (PCC) involves persistent symptoms three months post-infection, affecting 30%-50% of recovered individuals for up to two years. Risk factors include female sex, smoking, lung disease, and severe initial infection. This article examines if initial chest radiological findings predict PCC. Objective: This study aims to explore the association between initial chest radiological findings and the risk of PCC. Materials and Methods: A single-center ambidirectional cohort study included 1063 COVID-19 patients with thoracic imaging within 72 hours of admission. Baseline data, clinical symptoms, and imaging findings were collected. Six-month follow-up telephone interviews assessed persistent symptoms and PCC development. Results: 47.1% of patients developed PCC and 35% of these patients showed abnormalities in X-ray. Abnormal chest X-ray findings (RR: 1.19; 95%CI: 1.04-1.35), particularly ground glass opacities (RR: 1.18; 95%CI: 1.03-1.36), and multilobar involvement (RR: 1.348; 95%CI: 1.080-1.682) were associated with PCC at 6 months. Conclusion: This study establishes a link between initial chest X-ray findings and PCC development. Despite limited literature support, our findings stress the prognostic value of early imaging in predicting long-term outcomes. Further research is needed to validate imaging's role in understanding and predicting PCC.

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Association Between Chest Imaging and Persistent Symptoms: A Six-Month Follow-Up Study on COVID-19 SurvivorsChest imaging and COVID-19 persistent symptoms at six months follow-up.

Mantilla,

Ramirez,

Gutierrez

et al. 2024

Preprint

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Factors associated with long COVID syndrome in a Colombian cohort

Martínez-Ayala,

Proaños,

Cala-Duran

et al. 2023

Front. Med.

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IntroductionAfter acute phase of SARS-CoV-2 infection, some patients persist with clinical symptoms, a phenomenon known as Long COVID syndrome. It is necessary to understand the factors associated with the persistence of these symptoms to develop individualized preventive approaches and effectively address this challenge.ObjectiveTo determine the factors associated with the persistence of symptoms six months after COVID-19 infection.Materials and methodsA ambidirectional cohort, single-center study, that included individuals previously diagnosed with COVID-19 by real-time polymerase chain reaction (PCR) positive test, who were followed for a period of six months. Univariate, bivariate and a multivariate binomial regression model were performed to determine risk factors associated with the persistence of COVID-19 symptoms at the six months of follow-up.ResultsThe prevalence of long COVID syndrome was 47%. Age demonstrated no significant association with Long COVID (RR 0.999 [95% CI 0.996–1.002]); however, female sex (RR 1.148 [95% CI 1.038–1.268]), requirement of mechanical ventilation (RR 1.278 [95% CI 1.050–1.555]), presence of Chronic Obstructive Pulmonary Disease (COPD) (RR 1.340 [95% CI 1.104–1.626]), Rheumatic Disease (RR 1.259 [95% CI 1.055–1.504]) and the Hospitalization Type: General Hospitalization (RR 1.247 [95% CI 1.090–1.427]) and ICU Hospitalization (RR 1.490 [95% CI 1.221–1.818]) were significantly associated with the persistence of symptoms at the six month of follow-up.ConclusionFemale sex, presence of COPD, rheumatic disease, hospitalization type and requirement of mechanical ventilation during index infection were identified as significant risk factors for the diagnosis of Long COVID. These findings emphasize the importance of addressing Long COVID syndrome in terms of prevention and management, taking these risk factors into consideration.

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Variables Associated With In-Hospital Lethality in COVID-19: A Prospective Cohort Study From Colombia

Lora Mantilla,

Cáceres Ramírez,

Riaño Duarte

et al. 2024

Cureus

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Introduction: The emergence of COVID-19 represents the most significant health crisis in recent history. Incidence and mortality rates depend on several factors. Many studies have focused on investigating which characteristics could be strongly related to higher mortality and lethality. Objective: This study aims to analyze the variables associated with in-hospital mortality among patients admitted in a reference northeastern region of a Colombian institution. Methods: An ambidirectional cohort, single-center study was carried out in a reference hospital in northeastern Colombia. All patients admitted to the Fundación Oftalmológica de Santander (FOSCAL) between March 2020 and September 2021, with COVID-19 real-time polymerase chain reaction (PCR) positive test, were included. Results: A total of 3,028 patients were included, of whom 2,034 (67.8%) survived and 994 (32.8%) died during their hospital stay; 48.8% (1,479) of the patients were female. The most common comorbidities were hypertension (1,236 patients, 40.8%), obesity (body mass index (BMI) ≥ 30; 656 patients, 21.6%), and diabetes (618 patients, 20.4%). The average age of the surviving patients was 52.2 years, while for the deceased patients, it was 70.3 years. The variables that showed significant association with in-hospital mortality were as follows: male sex ≥ 45 years, dyspnea, oxygen saturation (SatO2) < 85%, hypertension, chronic kidney disease (CKD), and a Charlson Comorbidity Index (CCI) score of >1. Conclusions: Male sex, age ≥ 45 years, dyspnea, SatO2 < 85%, hypertension, CKD, and a CCI score of >1 were associated with a higher risk of in-hospital mortality in COVID-19-infected patients.

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General Hospitalization and Intensive Care Unit-Related Factors of COVID-19 Patients in Northeastern Colombia: Baseline Characteristics of a Cohort Study

Cited by 3 publications

References 40 publications

Association Between Chest Imaging and Persistent Symptoms: A Six-Month Follow-Up Study on COVID-19 SurvivorsChest imaging and COVID-19 persistent symptoms at six months follow-up.

Association Between Chest Imaging and Persistent Symptoms: A Six-Month Follow-Up Study on COVID-19 SurvivorsChest imaging and COVID-19 persistent symptoms at six months follow-up.

Factors associated with long COVID syndrome in a Colombian cohort

Variables Associated With In-Hospital Lethality in COVID-19: A Prospective Cohort Study From Colombia

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