General illness and psychological factors in patients with chronic nasal symptoms

Kara, Naveed; Yao, Alexander; Newton, Julia L.; Deary, Vincent; O’Hara, James; Wilson, Janet A.

doi:10.1111/coa.13032

Cited by 15 publications

(19 citation statements)

References 70 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…We also found that sleep disorders can cause anxiety and depression in CRS patients, which is consistent with the conclusions of many studies (6,10,12,36,37) . Earlier studies have found that the proportion of CRS patients with sleep disorders can reach 60-75%, which is much higher than that of the normal population (6,38,39) .…”

Section: Discussionsupporting

confidence: 92%

“…At the first visit, the patients were asked to complete the Nasal Sinus Outcome Test-20 (SNOT-20); the score was divided into nasal symptoms (0-18 points), facial/ear symptoms (0-12 points), sleep (0-12 Points) and emotional disorders (0-18 points) (12,19) ; and a CT scan of the sinuses was performed, in which the Lund-Mackay CT score (20) was used to evaluate the inflammation of the bilateral maxillary sinuses, anterior and posterior ethmoid sinuses, frontal sinuses, sphenoid sinuses, and ostiomeatal complexes (OMCs) (unilateral score range 0-12 points, 0-2 points for each item); and video endoscopy was performed, in which the Lund-Kennedy Nasal endoscopy score (20) was used to evaluate patients' bilateral polyps, edema, rhinorrhea, scars and scabs (unilateral score range 0-10 points, each score 0-2 points).…”

Section: Crs Severity Evaluationmentioning

confidence: 99%

“…The existence of anxiety and depression will enhance the patient's perception of local symptoms of CRS (such as oropharynx and facial discomfort) and systemic symptoms (fatigue and decreased sexual function), which will increase the use of antibiotics and affect work and life. Anxiety and depression have a great impact on the patient's quality of life (QoL) (11)(12)(13) , and bring certain challenges to the treatment of the disease (13)(14)(15) . Therefore, it is beneficial to identify CRS patients with a potential risk of anxiety and depression, that may have a reduction in QoL.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Associations of Symptomatic- and Anatomical-Based Severity of Chronic Rhinosinusitis With Patients' Anxiety and Depression

Lei

Sun

Yao

et al. 2021

Preprint

View full text Add to dashboard Cite

Background Patients with chronic rhinosinusitis (CRS) have a high incidence rate of anxiety and depression. However, changes in anxiety and depression with different severities of CRS,and the effects of symptoms and anatomical factors on the anxiety and depression of CRS patients remain unclear.Methods A total of 112 patients were enrolled in the study. The Sino-Nasal Outcome Test-20 (SNOT-22) score, Lund-Mackay scale and Lund-Kennedy scale were used to assess the severity of CRS, and the Generalized Anxiety Disorder-7 (GAD-7) and Patient Health Questionnaire-9 (PHQ-9) were used to evaluate anxiety and depression in patients. Results In the univariate analysis, SNOT-20 scores, nasal symptom scores, facial/ear symptom scores and sleep scores are significantly positively correlated with patients’ GAD-7 scores (all P<0.05); the patients’ SNOT-20 scores, nasal symptom scores, facial/ear symptom scores, sleep scores, and the higher side of the anterior ethmoid sinus and frontal sinus Lund-Mackay scores were significantly positively correlated with the patients’ PHQ-9 scores (all P<0.05). In a multivariate linear regression model, however, none of the covariates were found to be statistically associated with GAD-7. Another multivariate model indicated associations among the SNOT-20 sleep domain scores, the higher side of frontal sinus Lund- Mackay scores and PHQ-9 scores (both P < 0.01). Conclusions Exacerbated nasal and facial/ear symptoms, sleep dysfunction increase patients’ depression and anxiety. Lesions of the frontal sinus and anterior ethmoid sinus may be related to patients' depression. Treatment should be tailored to patients with these symptoms.

show abstract

Section: Discussionsupporting

confidence: 92%

Section: Crs Severity Evaluationmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Associations of Symptomatic- and Anatomical-Based Severity of Chronic Rhinosinusitis With Patients' Anxiety and Depression

Lei

Sun

Yao

et al. 2021

Preprint

View full text Add to dashboard Cite

show abstract

“…Patients with comorbid depression have been shown to have comparable overall gains from treatment as compared with healthy controls but worse baseline and posttreatment scores. 2,19 This is significant for a subspecialty where efficacy is somewhat determined by patient-reported treatment outcomes in a health care system with increasing emphasis on patient satisfaction and how it relates to reimbursements. Therefore, the underlying effect of psychiatric conditions, such as depression on CRS, must be considered in patient evaluations, and the physician should have a low threshold to ask the patient about psychiatric symptoms or need for psychiatry referral.…”

Section: Discussionmentioning

confidence: 99%

“…SNOT-22 scores in healthy adults have been reported to be between 7 and 9.3. [16][17][18][19] Furthermore, in 2017 Feng et al analyzed the SNOT-22 and found 4 distinct constructs that the questionnaire measuresspecifically, they divided the test into 4 subdomains based on the symptoms included in each category (nasal, otologic/ facial, emotional, and sleep). 20…”

Section: -Item Sinonasal Outcome Testmentioning

confidence: 99%

PHQ‐9 and SNOT‐22: Elucidating the Prevalence of Depression in Chronic Rhinosinusitis

Vandelaar

Jiang

Saini

et al. 2019

Otolaryngol.--head neck surg.

View full text Add to dashboard Cite

Objective Chronic rhinosinusitis (CRS) has been associated with comorbid depression, yet the prevalence of depression among all patients with CRS is not well described. The Patient Health Questionnaire–9 (PHQ-9), a validated instrument for diagnosing depression, has been used to assess depression in a variety of clinical settings. PHQ-9 scores ≥10 are the threshold for a depression diagnosis. The purpose of this study was to assess the prevalence of depression in a rhinology practice and compare the PHQ-9 with the 22-item Sinonasal Outcome Test (SNOT-22). Study Design Retrospective chart review. Setting Tertiary rhinology practice. Subjects and Methods During the 2-month period ending April 30, 2018, all rhinology patients were asked to complete the PHQ-9 and SNOT-22. Results Among 216 patients, 46 (21.3%) had a self-reported history of depression, and 39 (18.1%) had a PHQ-9 score ≥10. Of the 39 patients screening positive for depression, 18 (41.9%) had no history of depression. Comparison of PHQ-9 with overall SNOT-22 score had a Pearson’s coefficient of 0.632 ( P < .005). Logistic regression showed that the highest 2 quintiles of SNOT-22 scores had an odds ratio of 60.6 (95% CI, 9.7-378.3) for a positive depression screen (PHQ-9 score ≥10). Conclusion Depression rates (estimated by PHQ-9 responses) among rhinology patients are similar to chronic disease populations; depression may be underdiagnosed in rhinology patients. Higher SNOT-22 scores were associated with higher PHQ-9 scores. Further studies are warranted to understand the impact of comorbid conditions of depression and CRS in patient quality of life.

show abstract

Measurement Properties of the Patient Health Questionnaire–15 and Somatic Symptom Scale–8

Hybelius,

Kosic,

Salomonsson

et al. 2024

JAMA Netw Open

View full text Add to dashboard Cite

ImportanceThe subjective experience of somatic symptoms is a key concern throughout the health care system. Valid and clinically useful instruments are needed.ObjectiveTo evaluate the measurement properties of 2 widespread patient-reported outcomes: the Patient Health Questionnaire–15 (PHQ-15) and Somatic Symptom Scale–8 (SSS-8).Data SourcesMedline, PsycINFO, and Web of Science were last searched February 1, 2024.Study SelectionEnglish-language studies reporting estimates pertaining to factor analysis, taxometric analysis, internal consistency, construct validity, mean scores in relevant groups, cutoffs, areas under the receiver operating characteristic curves (AUROCs), minimal clinically important difference, test-retest reliability, or sensitivity to change.Data Extraction and SynthesisSearch hits were reviewed by independent raters. Cronbach α, Pearson r, means, and between-group effect sizes indicative of sensitivity to change were pooled in random-effects meta-analysis. Study quality was assessed using 3 instruments. Reporting followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses 2020 reporting guideline.Main Outcomes and MeasuresComprehensive overview of evidence pertaining to the measurement properties of the PHQ-15 and SSS-8.ResultsA total of 305 studies with 361 243 participants were included. Most concerned routine care (178 studies) and the general population (27 studies). In factor analyses, both scales reflected a combination of domain-specific factors (cardiopulmonary, fatigue, gastrointestinal, pain) and a general symptom burden factor. The pooled PHQ-15 α was 0.81 (95% CI, 0.80-0.82), but with low item-total correlations for items concerning menstrual problems, fainting spells, and sexual problems (item-total correlations &lt;0.40), and the SSS-8 α was 0.80 (0.77-0.83). Pooled correlations with other measures of somatic symptom burden were 0.71 (95% CI, 0.64-0.78) for the PHQ-15 and 0.82 (95% CI, 0.72-0.92) for the SSS-8. Reported AUROCs for identification of somatoform disorders ranged from 0.63 (95% CI, 0.50-0.76) to 0.79 (95% CI, 0.73-0.85) for the PHQ-15 and from 0.71 (95% CI, 0.66-0.77) to 0.73 (95% CI, 0.69-0.76) for the SSS-8. The minimal clinically important difference on both scales was 3 points. Test-retest reliability could not be pooled and was inconsistent for the PHQ-15 (PHQ-15: r = 0.65-0.93; ICC, 0.87; SSS-8: r = 0.996, ICC = 0.89). The PHQ-15 showed tentative sensitivity to change (g = 0.32; 95% CI, 0.08-0.56), but data for the SSS-8 were lacking.Conclusions and RelevanceIn this systematic review and meta-analysis, findings supported use of the PHQ-15 and SSS-8 for the assessment of symptom burden, but users should be aware of the complex, multifactorial structures of these scales. More evidence is needed concerning longitudinal measurement properties.

show abstract

General illness and psychological factors in patients with chronic nasal symptoms

Cited by 15 publications

References 70 publications

Associations of Symptomatic- and Anatomical-Based Severity of Chronic Rhinosinusitis With Patients' Anxiety and Depression

Associations of Symptomatic- and Anatomical-Based Severity of Chronic Rhinosinusitis With Patients' Anxiety and Depression

PHQ‐9 and SNOT‐22: Elucidating the Prevalence of Depression in Chronic Rhinosinusitis

Measurement Properties of the Patient Health Questionnaire–15 and Somatic Symptom Scale–8

Contact Info

Product

Resources

About