Delays in accessing care for young people with a first episode of psychosis are significantly associated with poorer treatment response and higher relapse rates.
AimTo assess the effect of an educational intervention for GPs on referral rates to early-intervention services and the duration of untreated psychosis for young people with first-episode psychosis.
Design of studyStratified cluster randomised controlled trial, clustered at practice level.
SettingBirmingham, England.
MethodPractices with access to the three early-intervention services in three inner-city primary care trusts in Birmingham were eligible for inclusion. Intervention practices received an educational intervention addressing GP knowledge, skills, and attitudes about first-episode psychosis. The primary outcome was the difference in the number of referrals to earlyintervention services between practices. Secondary outcomes were duration of untreated psychosis, time to recovery, use of the Mental Health Act, and GP consultation rate during the developing illness.
ResultsA total of 110 of 135 eligible practices (81%) were recruited; 179 young people were referred, 97 from intervention and 82 from control practices. The relative risk of referral was not significant: 1.20 (95% confidence interval [CI] = 0.74 to 1.95; P = 0.48). No effect was observed on secondary outcomes except for 'delay in reaching early-intervention services', which was statistically significantly shorter in patients registered in intervention practices (95% CI = 83.5 to 360.5; P = 0.002).
ConclusionGP training on first-episode psychosis is insufficient to alter referral rates to early-intervention services or reduce the duration of untreated psychosis; however, there is a suggestion that training facilitates access to the new specialist teams for early psychosis.
Keywordseducation; primary health care; psychosis.
INTRODUCTIONDuring the last two decades, the importance of intervening as early as possible when a young person develops a first episode of psychosis has become accepted internationally. This has been underpinned by studies demonstrating that young people with first-episode psychosis experience lengthy delays between the onset of psychotic symptoms and receipt of treatment (duration of untreated psychosis) of up to 2 years, 1-3 and that delays in accessing care are significantly associated with poorer treatment response. 4 There is a limited evidence base in this area of primary care, but GPs may be key to the identification and management of first-episode psychosis, as they are usually the first point of patient contact, 5 their involvement in the management of psychosis is associated with a reduction of the use of the Mental Health Act, 6 and they are the most common final referral agent to early-intervention services.7 However, early detection presents challenges as psychosis can take several months to emerge, 8 and may be difficult to distinguish from normal adolescent behaviour and substance misuse.9,10 There can be changes in