The masonry structure is one of the main types of modern industrial buildings in China because of its local materials and simple economy. However, these buildings often suffer damage and cracks due to uneven settlement of the foundation and disrepair, which affects the safe and normal use of the structure. It is urgent to maintain and strengthen the structure to restore the safety of the structure. This paper takes Baoji Shenxin Yarn Factory - Kiln Factory as the actual engineering background, and use the finite element software ABAQUS based on Winkler’s theory to establish a finite element calculation model that can more conveniently respond to the effects of different foundation settlements. Through the simulation analysis, the influence law of the local settlement of the kiln foundation on the overall structural force state was obtained, which can provide an important reference basis for the maintenance and reinforcement of the structure.