We obtain new generalized Hua’s inequality corresponding to YIV(N,n;K), where YIV(N,n;K) denotes the fourth Cartan-Hartogs domain in CN+n. Furthermore, we introduce the weighted Bloch spaces on YIV(N,n;K) and apply our inequality to study the boundedness and compactness of composition operator Cϕ from βp(YIV(N,n;K)) to βq(YIV(N,n;K)) for p≥0 and q≥0.