Generalized AA amyloidosis and fibrino-hemorrhagic pancreatitis in a Gazelle subgutturosa: a case report

Abstract

Generalized AA Amyloidosis and fibrino-hemorrhagic pancreatitis were diagnosed in a 6-year-old, male Gazelle subgutturosa submitted for necropsy from a Wild Animal Production Station in Malatya, a province from eastern Turkey. Adhesions between the visceral surfaces of abdominal organs including the liver, pancreas, diaphragma and spleen were observed in the necropsy. Microscopically, the mass consisted of fibrino-hemorrhagic pancreatic tissue. Chronic inflammatory reactions characterized by mononuclear cell infiltration and fibrous connective tissue proliferation were found on the serosal surface in the liver. Amyloid depositions were detected and confirmed by Congo red stained sections of the pancreas, liver, kidneys, and spleen viewed under a polarized light microscope. Generalized AA amyloidosis was thought to responsible for a chronic inflammation characterized by adhesions in Gazelle subgutturosa. Generalized AA amyloidosis along with pancreatic involvement and fibrinohemorrhagic changes are described for the first time in the Gazelle subgutturosa species.

Bir Ceylanda (Gazella gazella) Generalize Reaktif Amiloidoz Olgusu

“…Çeribaşı ve ark. [17] bir İran ceylanında fibrino- Amiloidoz şüpheli dokuların nekropsi sonrası Lugol ve sülfirik asit ile muamele edildiğinde amiloid birikimlerinin mavi renkte görüldüğü bildirilmektedir [1] . Sunulan bu olguda amiloid birikimiyle ilgili organlarda makroskobik bir bulgu gözlenmemesi nedeniyle nekropsiden sonra bu uygulamaya gerek duyulmamıştır.…”