Abstract-The use of wavelets has become increasingly popular in the development of numerical schemes for the solution of partial differential equations (PDEs), especially for problems with local high gradient. In this work, the Galerkin Method has been adapted for the direct solution of differential equations in a meshless formulation using Daubechies wavelets and Deslauriers-Dubuc interpolating functions (Interpolets). This approach takes advantage of wavelet properties like compact support, orthogonality and exact polynomial representation, which allow the use of a multiresolution analysis. Several examples based on typical differential equations for beams and thin plates were studied successfully.Index Terms-Wavelets, interpolets, wavelet-galerkin method, beam on elastic foundation, thin plates.