2020
DOI: 10.1016/j.apmt.2019.100469
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Generating ready-to-implant anisotropic menisci by 3D-bioprinting protein-releasing cell-laden hydrogel-polymer composite scaffold

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Cited by 53 publications
(69 citation statements)
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“…During plotting, the needle diameter, layer thickness and speed for PCL printing were kept constant at 200 μm, 200 μm, and 180 mm/min, respectively. The fiber spacing was kept constant at 300 μm according to our previous research, which would provide better mechanical support for the scaffold, allow a suitable cell density, and facilitate the uniform distribution and contact of cells, thereby promoting cell viability and proliferation 20 , 21 . PLGA microspheres (μS) was used to deliver TGFβ3 and CTGF in the MSC-laden hydrogels.…”
Section: Resultsmentioning
confidence: 99%
“…During plotting, the needle diameter, layer thickness and speed for PCL printing were kept constant at 200 μm, 200 μm, and 180 mm/min, respectively. The fiber spacing was kept constant at 300 μm according to our previous research, which would provide better mechanical support for the scaffold, allow a suitable cell density, and facilitate the uniform distribution and contact of cells, thereby promoting cell viability and proliferation 20 , 21 . PLGA microspheres (μS) was used to deliver TGFβ3 and CTGF in the MSC-laden hydrogels.…”
Section: Resultsmentioning
confidence: 99%
“…BMSCs were acquired from mouse bone marrow as previously described [ 18 ]. Briefly, marrow aspirates (10-20 mL) were harvested and then transferred to plastic tubes.…”
Section: Methodsmentioning
confidence: 99%
“…Alternatively, the particles can be embedded into a hydrogel that is 3D printed between adjacent PCL filaments 103 . In this case, the hydrogel can be also used as a cell carrier 103 .…”
Section: Microparticle-loaded 3d Printed Scaffoldsmentioning
confidence: 99%
“…PCL) and a hydrogel component, benefiting from the mechanical resistance of the former and the cell-friendly environment of the latter. To this purpose, constructs can be fabricated by the deposition of adjacent filaments of PCL alternating with cell-laden hydrogel103 . Alternatively, pre-fabricated 3D printed constructs can be infused with cell-laden hydrogels.…”
mentioning
confidence: 99%