, he is interested in designing and building software systems to enable domain experts to easily access and effectively use high performance computing to perform and share the findings of simulations and large scale data analyses. Other aspects of his research focus on how to use these systems as learning tools for students and teachers.
Dr. Chris J. Kuhlman, Virginia Bioinformatics InstituteChris is a Research Scientist at the Biocomplexity Institute at Virginia Tech. His research interests include discrete dynamical systems, agent-based modeling and simulation, distributed and high performance computing, algorithms, social sciences and modeling, and network science. In the U.S., major depressive disorder affects approximately 14.8 million American adults. Furthermore, depression can lead to a several other illnesses and disabilities. Economic burden of depression is estimated to be $53 billion annually in the U.S. alone. Depression can reach high levels that can lead to suicide, the third leading cause of death among the U.S. college-aged population.Studies show a direct relation between mental health and academic success. In particular, depression is a significant predictor of lower GPA and increased drop out rate. A 15 point increase on the depression scale correlates with a 0.17 drop in GPA and corresponds to a 4.7 percent increase in probability of dropping out. High dropout rates also adversely impact both universities and society.In this work, we construct and exercise an agent-based model (ABM) of the evolution of depression among a population of roughly 19,000 college students. This model includes within-agent interactions among depression symptoms and agent-to-agent interactions defined by a college student social network. We conduct simulation studies to identify (model) parameters and initial conditions that most influence population outcomes. Connectivity among within-agent symptoms is demonstrated to have a large effect on population levels of depression.