Solid-state quantum registers are exceptional for storing quantum information at room temperature with long coherence time. Nevertheless, practical applications toward quantum supremacy require even longer coherence time to allow for more complex algorithms. In this work we propose a quantum register that lies in a decoherence-free subspace to be implemented with color centers in diamond. The quantum information is encoded in two logical states composed of two nearby nuclear spins, while an electron spin is used as ancilla for initialization and control. Moreover, by tuning an off-axis magnetic field we enable non-nuclear-spin-preserving transitions that we use for preparing the register through Stimulating Raman Adiabatic Passage. Furthermore, we use this sequence to manipulate the quantum register and an individual nuclear spin.