Genetic Ancestry and Health

Edinur, Hisham Atan; Chamber, Geoffrey Keith

doi:10.15406/moji.2017.05.00151

Cited by 3 publications

(1 citation statement)

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“…Extensive population genetic screening has been conducted in Peninsular Malaysia using genetic samples collected from Malays, Orang Asli (Proto-Malays, Semang and Senoi), Indians and Chinese (e.g. recently reviewed by Chambers, 2017 andNorhalifah et al, 2016a). The important finding from the research on the Malays and Orang Asli is that genes which are important in medical genetics have a whole different repertoire in various sub-populations in Peninsular Malaysia.…”

Section: Genetic Genealogy In Sabah and Sarawakmentioning

confidence: 99%

A New Analysis of Population History in Sabah and Sarawak

Hakim¹,

Lalung

Narayanen

et al. 2018

Global J. Bus. Soc. Sci. Review

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Objective - This study is a comprehensive account of contemporary knowledge concerning pre-historic communities in Sabah and Sarawak based on newly available evidence from genomic and archaeological research. Methodology/Technique - The data presented in this review was obtained from primary literature including recent reports on several Neolithic excavation sites including Gua Sireh, Bukit Tengkorak, Melanta Tutup, and Bukit Kamiri. Findings - Pre-neolithic populations existed in Borneo long before the arrival of Austronesians as is evident from Niah Cave remains. These considerably pre-date the arrival of the latter new immigrants around 3,500 years ago. Further genetic research is needed, as the current view of the history of the population is based on a limited number of ethnic groups among those currently living in Borneo and to date, no trace has been found of any surviving genetic lineages from the earliest settlers. Novelty - This review paints a contemporary picture from existing information. In particular, it highlights the need for further research on the topic, as the current view of the genetic history of the population in Sabah and Sarawak is only available on a limited number of ethnic groups currently living in Borneo. Developing a conclusive and composite view on this topic will require widespread genetic surveys of many more ethnic groups scattered throughout the Sabah and Sarawak areas. This will require large-scale next-generation techniques (such as genome-wide SNP surveys and whole genome sequencing etc.). These methods should be enhanced by examination of ancient materials including human remains and their associated artefacts. These initiatives will require a number of well-planned excavations of recent settlements (last 10,000 years) and the application of trace and ancient DNA methodology. Type of Paper - Review. Keywords: Population Genetics; Archaeology; Borneo; Sabah and Sarawak; Malaysia; Population History. JEL Classification: N90, Z10.

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Section: Genetic Genealogy In Sabah and Sarawakmentioning

confidence: 99%