Genetic and antigenic characterization of the first H7N7 low pathogenic avian influenza viruses isolated in Vietnam

Le, Kien; Okamatsu, Masatoshi; Hien, Nguyen Duc; Matsuno, Keita; Chu, Duc-Huy; Tien, Tien Ngoc; Le, Tung Thanh; Kida, Hiroshi; Sakoda, Yoshihiro

doi:10.1016/j.meegid.2019.104117

Cited by 7 publications

(8 citation statements)

References 43 publications

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“…These factors have contributed to the spread of these viruses to parts of Asia, Europe, Africa, and North America after an outbreak in wild birds at Qinghai Lake in China in 2005 [14]. Circulations of H7 LPAIVs in wild birds and poultry have been reported throughout the world [7,13,[15][16][17][18][19][20]. In addition, H7N9 HPAIVs and LPAIVs are at risk to spread by wild bird and human-caused movements [21,22].…”

Section: Discussionmentioning

confidence: 99%

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Genetic and antigenic characterization of H5 and H7 avian influenza viruses isolated from migratory waterfowl in Mongolia from 2017 to 2019

et al. 2020

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The circulation of highly pathogenic avian influenza viruses (HPAIVs) of various subtypes (e.g., H5N1, H5N6, H5N8, and H7N9) in poultry remains a global concern for animal and public health. Migratory waterfowls play important roles in the transmission of these viruses across countries. To monitor virus spread by wild birds, active surveillance for avian influenza in migratory waterfowl was conducted in Mongolia from 2015 to 2019. In total, 5000 fecal samples were collected from lakesides in central Mongolia, and 167 influenza A viruses were isolated. Two H5N3, four H7N3, and two H7N7 viruses were characterized in this study. The amino acid sequence at hemagglutinin (HA) cleavage site of those isolates suggested low pathogenicity in chickens. Phylogenetic analysis revealed that all H5 and H7 viruses were closely related to recent H5 and H7 low pathogenic avian influenza viruses (LPAIVs) isolated from wild birds in Asia and Europe. Antigenicity of H7Nx was similar to those of typical non-pathogenic avian influenza viruses (AIVs). While HPAIVs or A/Anhui/1/2013 (H7N9)related LPAIVs were not detected in migratory waterfowl in Mongolia, sporadic introductions of AIVs including H5 and H7 viruses into Mongolia through the wild bird migration were identified. Thus, continued monitoring of H5 and H7 AIVs in both domestic and wild birds is needed for the early detection of HPAIVs spread into the country.

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Section: Discussionmentioning

confidence: 99%

“…Other gene segments of H7N3 and H7N7 viruses were also classified with typical LPAIVs circulating in wild birds (Supplemental Figs. S1-S8) [13].…”

Section: Genetic and Phylogenetic Analysis Of H5 And H7 Subtype Virusesmentioning

confidence: 98%

Genetic and antigenic characterization of H5 and H7 avian influenza viruses isolated from migratory waterfowl in Mongolia from 2017 to 2019

et al. 2020

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“…During the annual surveillance of AIVs in poultry, H7 AIVs have been found to circulate in many countries, including Vietnam, Cambodia, the Netherlands, and China 1,15,16 . H7N9 AIV first infected humans in 2013, and has caused five epidemics in China.…”

Section: Discussionmentioning

confidence: 99%

Development of a monoclonal antibody‐based antigen capture enzyme‐linked immunosorbent assay for detection of H7N9 subtype avian influenza virus

Yang

Xiao

Liu

et al. 2020

Journal of Medical Virology

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To establish a rapid detection method for H7N9 avian influenza virus (AIV), monoclonal antibodies (mAbs) against hemagglutinin (HA) of H7N9 were developed to establish an antigen‐capture enzyme‐linked immunosorbent assay (AC‐ELISA). AC‐ELISA achieved high specificity and sensitivity, with a detection limit of 3.9 ng/mL for H7N9 HA protein (A/Zhejiang/DTID‐ZJU01/2013), and 2−2 HA unit/100 μL for live H7N9 AIV. The inter‐ and intra‐assay coefficient of variation was less than 10%. Compared with conventional virus isolation detection, the sensitivity and specificity were 94.96% and 88.24%, respectively. AC‐ELISA proved to be a rapid and practical technique for the detection of H7N9 AIV.

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“…Oropharyngeal swabs, cloacal swabs and faecal samples were collected from chickens, ducks and Muscovy ducks from each participant enterprise at each sampling round. The oropharyngeal and cloacal swabs from the same poultry were kept in one sterile tube containing transport medium, as described previously (Le et al., 2020). This medium comprised Eagle's minimum essential medium (Nissui, Japan) containing 10,000 U/ml penicillin G (Meiji Seika, Japan), 10 mg/ml streptomycin (Meiji Seika, Japan), 0.3 mg/ml gentamicin (Schering Plough, USA), 250 U/ml nystatin (Sigma, USA) and 0.5% bovine serum albumin fraction V (Roche, Switzerland).…”

Section: Methodsmentioning

confidence: 99%

A systematic approach to illuminate a new hot spot of avian influenza virus circulation in South Vietnam, 2016–2017

Stevenson

Isoda

et al. 2021

Transbounding Emerging Dis

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In South Vietnam, live bird markets (LBMs) are key in the value chain of poultry products and spread of avian influenza virus (AIV) although they may not be the sole determinant of AIV prevalence. For this reason, a risk analysis of AIV prevalence was conducted accounting for all value chain factors. A cross‐sectional study of poultry flock managers and poultry on backyard farms, commercial (high biosecurity) farms, LBMs and poultry delivery stations (PDSs) in four districts of Vinh Long province was conducted between December 2016 and August 2017. A total of 3597 swab samples were collected from birds from 101 backyard farms, 50 commercial farms, 58 sellers in LBMs and 19 traders in PDSs. Swab samples were submitted for AIV isolation. At the same time a questionnaire was administered to flock managers asking them to provide details of their knowledge, attitude and practices related to avian influenza. Multiple correspondence analysis and a mixed‐effects multivariable logistic regression model were developed to identify enterprise and flock manager characteristics that increased the risk of AIV positivity. A total of 274 birds were positive for AIV isolation, returning an estimated true prevalence of 7.6% [95% confidence interval (CI): 6.8%–8.5%]. The odds of a bird being AIV positive if it was from an LBM or PDS were 45 (95% CI: 3.4–590) and 25 (95% CI: 1.4–460), respectively, times higher to the odds of a bird from a commercial poultry farm being AIV positive. The odds of birds being AIV positive for respondents with a mixed (uncertain or inconsistent) level and a low level of knowledge about AI were 5.0 (95% CI: 0.20–130) and 3.5 (95% CI: 0.2–62), respectively, times higher to the odd of birds being positive for respondents with a good knowledge of AI. LBMs and PDSs should receive specific emphasis in AI control programs in Vietnam. Our findings provide evidence to support the hypothesis that incomplete respondent knowledge of AI and AIV spread mechanism were associated with an increased risk of AIV positivity. Delivery of education programs specifically designed for those in each enterprise will assist in this regard. The timing and frequency of delivery of education programs are likely to be important if the turnover of those working in LBMs and PDSs is high.

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Genetic and antigenic characterization of the first H7N7 low pathogenic avian influenza viruses isolated in Vietnam

Abstract: PB2 gene. Thus, these results highlight the need for continuous and intensive surveillance of avian influenza in Vietnam, targeting not only highly pathogenic AIVs but also low pathogenic viruses.

Cited by 7 publications

References 43 publications

Genetic and antigenic characterization of H5 and H7 avian influenza viruses isolated from migratory waterfowl in Mongolia from 2017 to 2019

Genetic and antigenic characterization of H5 and H7 avian influenza viruses isolated from migratory waterfowl in Mongolia from 2017 to 2019

Development of a monoclonal antibody‐based antigen capture enzyme‐linked immunosorbent assay for detection of H7N9 subtype avian influenza virus

A systematic approach to illuminate a new hot spot of avian influenza virus circulation in South Vietnam, 2016–2017

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