Genetic and Environmental Risk Factors for Factor VIII Inhibitor Development

Hemophilia in Iran

“…7 The incidence of inhibitors depends on several factors such as ethnicity, family history, HLA complex genotype, gene mutations, age at first treatment, intensity of treatment, and continuous infusions. 8,9 Iran has a great number of patients with hemophilia; based on population, it has one of the highest global incidences. A considerable number of studies, performed on different aspects of Iranian patients with hemophilia from 2001 to 2015, have been published in English and Persian languages.…”