“…As a matter of fact, the pathogenetic importance of epigenetic dysregulation - first revealed by cancer researchers [17] - has been realized by now in all major domains of medicine. Epigenetic research significantly contributed not only to the understanding of key pathogenetic events occurring in rare diseases like ICF syndrome (immunodeficiency, centromere instability, facial abnormalities; a chromatin disorder of gene silencing), Rett syndrome (associated with the dysfunction of a methyl-CpG-binding protein), and imprinting disorders, but also facilitated the molecular characterization of high-prevalence diseases such as autoimmune syndromes, major psychiatric syndromes, atherosclerosis and malignant tumors including glioblastoma multiforme, lung carcinoma, breast cancer, and prostate cancer [18,19,20,21,22,23,24,25,26,27,28]. …”