2024
DOI: 10.3390/diagnostics14242769
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Genetic Associations of TCF7L2 (rs7903146) and PPARG (rs1801282) with Prediabetes in the Ethnic Kazakh Population

Azhar Dyussupova,
Gulnara Svyatova,
Galina Berezina
et al.

Abstract: Background: This study aims to investigate the genetic contribution of polymorphic variants of the TCF7L2 (rs7903146) and PPARG (rs1801282) genes to the risk of developing prediabetes in individuals of Kazakh ethnicity. Materials and Methods: This was a case-control study involving 200 cases with prediabetes and 200 prediabetes-free controls, aged 16–60 years (n = 400). Real-time polymerase chain reaction on a StepOnePlus instrument (Applied Biosystems, USA), employing the TaqMan method for site-specific ampli… Show more

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