Genetic data from Y chromosome STR and SNP loci in Ukrainian population

Mielnik-Sikorska, Marta; Daca, Patrycja; Woźniak, Marcin; Malyarchuk, B. A.; Bednarék, J; Dobosz, Tadeusz; Grzybowski, Tomasz

doi:10.1016/j.fsigen.2012.05.007

Cited by 20 publications

(11 citation statements)

References 23 publications

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“…Studies on Y-chromosome indicate the composite regional background of paternal gene pools (e.g. R1a, I lineages) and the substantial substructure of eastern European populations [15]–[29].…”

Section: Introductionmentioning

confidence: 99%

Uniparental Genetic Heritage of Belarusians: Encounter of Rare Middle Eastern Matrilineages with a Central European Mitochondrial DNA Pool

et al. 2013

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Ethnic Belarusians make up more than 80% of the nine and half million people inhabiting the Republic of Belarus. Belarusians together with Ukrainians and Russians represent the East Slavic linguistic group, largest both in numbers and territory, inhabiting East Europe alongside Baltic-, Finno-Permic- and Turkic-speaking people. Till date, only a limited number of low resolution genetic studies have been performed on this population. Therefore, with the phylogeographic analysis of 565 Y-chromosomes and 267 mitochondrial DNAs from six well covered geographic sub-regions of Belarus we strove to complement the existing genetic profile of eastern Europeans. Our results reveal that around 80% of the paternal Belarusian gene pool is composed of R1a, I2a and N1c Y-chromosome haplogroups – a profile which is very similar to the two other eastern European populations – Ukrainians and Russians. The maternal Belarusian gene pool encompasses a full range of West Eurasian haplogroups and agrees well with the genetic structure of central-east European populations. Our data attest that latitudinal gradients characterize the variation of the uniparentally transmitted gene pools of modern Belarusians. In particular, the Y-chromosome reflects movements of people in central-east Europe, starting probably as early as the beginning of the Holocene. Furthermore, the matrilineal legacy of Belarusians retains two rare mitochondrial DNA haplogroups, N1a3 and N3, whose phylogeographies were explored in detail after de novo sequencing of 20 and 13 complete mitogenomes, respectively, from all over Eurasia. Our phylogeographic analyses reveal that two mitochondrial DNA lineages, N3 and N1a3, both of Middle Eastern origin, might mark distinct events of matrilineal gene flow to Europe: during the mid-Holocene period and around the Pleistocene-Holocene transition, respectively.

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Section: Introductionmentioning

confidence: 99%

Uniparental Genetic Heritage of Belarusians: Encounter of Rare Middle Eastern Matrilineages with a Central European Mitochondrial DNA Pool

et al. 2013

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“…The highest frequency of R1a-M458 was found in Poles, Czechs, Slovaks and Western Belarusians (>20%). Among Eastern and Western Slavic populations it is observed at frequencies higher than 10%, whereas elsewhere References: Latvians -present study; Ukrainians (Mielnik-Sikorska et al, 2013); Belarusians (Kushniarevich et al, 2013); Russians Northern/Central (Balanovsky et al, 2008); Estonians, Lithuanians, Finns, Karelians (Lappalainen et al, 2008); Swedes (Karlsson et al, 2006); South Siberian populations (Derenko et al, 2006); Maris from the Volga-Ural region (Tambets et al, 2004); Poles, Germans (Rebala et al, 2012); populations from Iberian Peninsula and samples from France/Corsica (Bekada et al, 2013). References: Latvians -present study; Estonians, Lithuanians, Finns, Karelians (Lappalainen et al, 2008); Swedes (Karlsson et al, 2006).…”

Section: Nry Lineages Of a Latvian Population In The Context Of Neighmentioning

confidence: 59%

“…As hg N1c is frequently found among FinnoUgric-speaking Finns, Saami, Karelians, Estonians, as well among Lithuanians and Northern Russians, North-Eastern Europe might be a source of the secondary expansion of this lineage (Zerjal et al, 1997;Lahermo et al, 1999;Zerjal et al, 2001;Laitinen et al, 2002;Tambets et al, 2004;Rootsi et al, 2007;Lappalainen et al, 2008). The frequency drops drastically in the neighboring populations of the Baltic-speaking Latvians and Lithuanians: in Poles (2%-3%), Ukrainians (0%-11%) and Belarusians (9.6%); nonetheless, Northern Russians (29%-36%) and Central Russians (16%) possess this Y-chromosomal variant at a relatively high frequency (Rosser et al, 2000;Tambets et al, 2004;Balanovsky et al, 2008;Lappalainen et al, 2008;Rebala et al, 2012;Kushniarevich et al, 2013;Mielnik-Sikorska et al, 2013). Kasperaviciute et al (2004) found differences in the variance of the N1c Y-STR between Baltic-and Finno-Ugric-speakers of the region: the 15 repeat STR marker DYS19 was more frequent in Lithuanians (93%) and Latvians (80.6%), whereas the same variant was significantly (p ࣘ 0.05) less frequent among Estonians (25.0%), and even less so among Finns (9.3%).…”

Section: Nry Lineages Of a Latvian Population In The Context Of Neighmentioning

confidence: 99%

Y‐Chromosomal Lineages of Latvians in the Context of the Genetic Variation of the Eastern‐Baltic Region

Pliss

Timša

Rootsi

et al. 2015

Annals of Human Genetics

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Variations of the nonrecombining Y-chromosomal region were investigated in 159 unrelated Baltic-speaking ethnic Latvians from four different geographic regions, using 28 biallelic markers and 12 short tandem repeats. Eleven different haplogroups (hgs) were detected in a regionally homogeneous Latvian population, among which N1c, R1a, and I1 cover more than 85% of its paternal lineages. When compared its closest geographic neighbors, the composition of the Latvian Y-chromosomal gene pool was found to be very similar to those of Lithuanians and Estonians. Despite the comparable frequency distribution of hg N1c in Latvians and Lithuanians with the Finno-Ugric-speaking populations from the Eastern coast of the Baltic Sea, the observed differences in allelic variances of N1c haplotypes between these two groups are in concordance with the previously stated hypothesis of different dispersal ways of this lineage in the region. More than a third of Latvian paternal lineages belong specifically to a recently defined R1a-M558 hg, indicating an influence from a common source within Eastern Slavic populations on the formation of the present-day Latvian Y-chromosome gene pool.

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“…All values were mapped using Surfer 6 and are reported in Supporting Information S‐Table 5. The references used for this analysis were: Alakoc et al, , Alves et al, , Belyaeva et al, 2003, Bosch et al, 2006, Brisighelli et al, 2012, Carvalho et al, , Cerri et al, , De Maesschalck et al, , Gaibar et al, , Garcia et al, , Ghiani and Vona , Grignani et al, , Gršković et al, , Henke et al, , Holmlund et al, , Karlsson et al, , Kayser et al, , Kovatsi et al, , Laouina et al, , Mielnik‐Sikorska et al, , Ploski et al, , Robino et al, , Roewer et al, , Roewer et al, , Roewer et al, , Stanciu et al, , Valverde et al, , Veselinovic et al, . White circles denote the location of populations used in the Y chromosome analysis.…”

Section: Resultsmentioning

confidence: 99%

Traces of forgotten historical events in mountain communities in Central Italy: A genetic insight

Messina

Finocchio

Rolfo

et al. 2015

American J Hum Biol

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Genetic data from Y chromosome STR and SNP loci in Ukrainian population

Cited by 20 publications

References 23 publications

Uniparental Genetic Heritage of Belarusians: Encounter of Rare Middle Eastern Matrilineages with a Central European Mitochondrial DNA Pool

Uniparental Genetic Heritage of Belarusians: Encounter of Rare Middle Eastern Matrilineages with a Central European Mitochondrial DNA Pool

Y‐Chromosomal Lineages of Latvians in the Context of the Genetic Variation of the Eastern‐Baltic Region

Traces of forgotten historical events in mountain communities in Central Italy: A genetic insight

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