Genetic Diversity and Trends of Ancestral and New Inbreeding in Deutsch Drahthaar Assessed by Pedigree Data

Michels, Paula Wiebke; Distl, O.

doi:10.3390/ani12070929

Cited by 8 publications

(7 citation statements)

References 36 publications

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“…This could be due to selection pressure, with some animals or families being preferred more than others [ 56 ]. Similar findings were reported for Dogue de Bordeaux dogs [ 46 ] and Bracco Italiano dogs [ 44 ], but these were lower than those of the ancestors of Deutsch Drahthaar dogs [ 57 ]. In this study, male ancestors contributed 10.67% to the total genetic variation, which was similar to the findings of Brito et al [ 58 ] and Sölkner et al [ 59 ] for Austrian Braunvieh, Pinzgauer, and Grauvier cattle populations, where an influential ancestor contributed close to 10% to the total genetic variation.…”

Section: Discussionsupporting

confidence: 84%

Pedigree-Based Genetic Diversity in the South African Boerboel Dog Breed

Mabunda,

Nephawe,

Mtileni

et al. 2024

Animals

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The Boerboel dog breed (BBD) is indigenous to South Africa (SA) and plays an important role in safeguarding homes and farms. The Department of Agriculture, Land Reform, and Rural Development (DALRRD) classifies the BBD as a protected species, and it is valued for its intelligence, boldness, and strength, as well as for continually ensuring the safety of its owners. The aim of this study was to investigate genetic diversity within the BBD population using pedigree information. The original BBD data, which contained 87,808 records, were obtained from the Integrated Registration and Genetic Information System (INTERGIS). After editing, the pedigree data included 87,755 records of animals born between 1971 and 2019. Pedigree analyses were performed using PEDIG (Fortran 77 software) to determine the completeness, inbreeding coefficients, and genetic diversity as defined by the genetic contributions of the most important ancestors of the current animals. This study identified 91.2% inbred animals in the BBD population, with an average and maximum inbreeding of 7.5% and 50% of inbred animals, respectively. The estimated inbreeding rate per year was 0.20% with an effective population size of 83.1. The most influential ancestors explained 82.63% and 80.92% of the total genetic variation for males and females in the studied populations, respectively. Only 10 important ancestors explained more than 50% of the entire population’s genetic diversity. The numbers of founders (f) were 348 and 356, and the effective numbers of founders (fe) were 57.4 and 60.1, respectively, for males and females. The numbers of founders were higher than the effective numbers of founders, implying a loss of genetic diversity due to unequal founder contributions. The BBD population was not critically endangered based on the inbreeding rates and effective population size; however, the population experienced a significant loss of genetic variability, unequal genetic contributions by founders, and a genetic bottleneck. Future breeding strategies could benefit from using equal proportions of parent stock and including new genetically distant breeds.

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Section: Discussionsupporting

confidence: 84%

Pedigree-Based Genetic Diversity in the South African Boerboel Dog Breed

Mabunda,

Nephawe,

Mtileni

et al. 2024

Animals

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“…Quando estes parâmetros gerais são comparados com dados da literatura, que também avaliaram endogamia utilizando dados de pedigree, é possível perceber que esta amostra da raça, nascida entre 1965 e 2019 em 17 países, Página 109 possui níveis baixos de endogamia, demonstrando um bom controle de acasalamentos endogâmicos. Outros estudos utilizando a mesma abordagem detectaram valores médios superiores aos encontrados na presente amostra (LEROY et al, 2006;CALBOLI et al, 2008;MICHELS;DISTL, 2022). Especificamente para outras populações de Labrador, valores médios de 2,4% a 3,4% já foram detectados em populações do Reino Unido e Austrália (CALBOLI et al, 2008;SHARIFLOU et al, 2011).…”

Section: Resultsunclassified

“…Foi possível detectar que este incremento foi de 0.042% na média do valor de F ao ano (p<0,001). Este parâmetro também é inferior àquele já detectado em outras populações (LEROY et al, 2006;CALBOLI et al, 2008;MICHELS;DISTL, 2022), o que pode também ser resultado de um menor volume de dados. A endogamia foi comparada entre países de nascimento, de forma que a Figura 2 demonstra a distribuição destes valores de acordo com regiões de nascimentos dos cães (conforme descrito em material e métodos).…”

Section: Resultsunclassified

Avaliação Da Endogamia Em Criações Nacionais De Labrador Retriever

Andrade¹,

Jardim²,

Scabello³

et al. 2022

Pesquisas E Inovações Em Ciências Agrárias: Produções Científicas Multidisciplinares No Século XXI, Volume 3

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RESUMO:O Brasil figura em segundo lugar no mercado mundial de produtos pet, com uma população de mais de 52 milhões de caninos, sendo o Labrador Retriever uma raça com grande popularidade. No Brasil é uma das raças de grande porte mais comercializada, com mais de mil cães ao ano sendo oficialmente registrados na última década. A prática de acasalamentos endogâmicos é historicamente bastante difundida na cinofilia, com uma tendência atual de maior controle e limitação por parte de criadores de países desenvolvidos. No entanto, uma vez que o campo de pesquisa em melhoramento genético de caninos é pouco explorado no Brasil, não existem dados que demonstrem se este cuidado com o nível de endogamia excessivo já está sendo aplicado na criação nacional, e qual o status dos caninos nascidos no Brasil com relação a este parâmetro. Desta forma, objetivou-se avaliar a taxa de endogamia de cães de cinco canis pertencentes ao Clube Paulista do Labrador, comparando valores do coeficiente de endogamia (F) entre canis, e dos cães nascidos no Brasil com aqueles originários de outros países. A partir de dados do site k9data.com, foram cadastradas cinco gerações de oitenta cães, totalizando um banco com 1.128 cães, sendo 184 nascidos no Brasil e o restante em 17 outros países. Os parâmetros populacionais foram obtidos com os softwares CFC e POPREP. Valores de F foram comparados entre canis e entre países através de Kruskal Wallis, utilizando o pacote R. O valor médio de F de toda a amostra foi de 0,61%, sendo 17,1% dos cães endogâmicos, mas somente 1,24% desses animais apresentaram valores de F acima de 10% (14 cães) Valores médios de F tiveram seu pico nos anos de 2015 e 2019. Quando a origem dos animais foi avaliada, foi possível detectar que cães nascidos no Brasil (F médio de 2,004%) tiveram valores de F significativamente maiores do que aqueles nascidos nas outras quatro áreas geográficas (F médio de 0,528%, p<0,0001). Diante da confirmação do não acompanhamento da tendência mundial, nós concluímos haver a necessidade de inclusão de mão de obra técnica para aconselhamento genético na criação de cães nacional, o que poderia auxiliar no controle eficiente da endogamia da raça.

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“…The first step in any biodiversity preservation program and in genetic improvement strategies is to understand the demographic and genealogical structure. Despite the widespread use of modern molecular analysis, the genetic variability of a population is still evaluated through pedigree analysis in both livestock [20][21][22] and pets [23][24][25]. The puberty of Massese ewes occurs at 6-8 months and the first lamb at about 15-18 months.…”

Section: Introductionmentioning

confidence: 99%

Demography and Genealogical Analysis of Massese Sheep, a Native Breed of Tuscany

Giuliotti,

Benvenuti,

Preziuso

et al. 2024

Animals

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This study investigates the genealogical and demographic trends of the Massese sheep breed in Tuscany from 2001 to 2021. The Herd Book kept by the Italian Sheep and Goat Breeders Association (Asso.Na.Pa) provided the data. The descriptive statistics were analyzed using JMP software. The pedigree parameters of a total of 311,056 animals (whole population—WP) were analyzed using CFC, ENDOG, and Pedigree viewer software. A total of 24,586 animals born in the period 2007–2021 represented the Reference Population (RP), and 18,554 animals the Base Population (BP). The demographic results showed an inconsistent trend of offspring registration. This study showed a short period of productivity for both ewes and rams, with means of 1.47 and 19.2 registered newborn ewes and rams, respectively. The genealogical analysis revealed incomplete data, highlighting inaccurate assessments of the relationships among the animals, and inbreeding with large differences among provinces. The average inbreeding coefficient in the WP was 1.16%, and it was 2.26% in the RP. The total number of inbreds was 2790 in the WP, with an average FPED of 13.56%, and 2713 in the RP, with an average FPED of 12.82%. The use of pedigree data is a key and economical approach to calculating inbreeding and relationship coefficients. It is the primary step in genetic management, playing a crucial role in the preservation of a breed. The regular updating of genealogical data is the first step to ensuring the conservation of animal genetic resources, and this study is compromised by the lack of such updates.

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Genetic Diversity and Trends of Ancestral and New Inbreeding in Deutsch Drahthaar Assessed by Pedigree Data

Cited by 8 publications

References 36 publications

Pedigree-Based Genetic Diversity in the South African Boerboel Dog Breed

Pedigree-Based Genetic Diversity in the South African Boerboel Dog Breed

Avaliação Da Endogamia Em Criações Nacionais De Labrador Retriever

Demography and Genealogical Analysis of Massese Sheep, a Native Breed of Tuscany

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