2021
DOI: 10.1007/s12035-020-02239-z
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Genetic Diversity of SARS-CoV2 and Environmental Settings: Possible Association with Neurological Disorders

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Cited by 34 publications
(6 citation statements)
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“…The outbreak soon spread all over the world and the World Health Organization (WHO) soon declared it a global pandemic (Yasir et al 2020 ; Kumar et al 2021 ). There is virtually no country in the world that has not been affected by this pandemic (El-Sayed et al 2021 ; Hasana et al 2021 ). As of 5th June 2021, the number of confirmed COVID-19 cases reached 173 M, with 3.72 M reported deaths (Worldometers 2020 ).…”
Section: Introductionmentioning
confidence: 99%
“…The outbreak soon spread all over the world and the World Health Organization (WHO) soon declared it a global pandemic (Yasir et al 2020 ; Kumar et al 2021 ). There is virtually no country in the world that has not been affected by this pandemic (El-Sayed et al 2021 ; Hasana et al 2021 ). As of 5th June 2021, the number of confirmed COVID-19 cases reached 173 M, with 3.72 M reported deaths (Worldometers 2020 ).…”
Section: Introductionmentioning
confidence: 99%
“…The clinical results of COVID-19 on patients with cardiovascular diseases and cardiopulmonary injuries have been reported [2]. COVID-19 accelerates the pathogenesis of the neurological disorders, although the pathogenic mechanisms between COVID-19 and neurological disorders are not very clear [3].…”
Section: Sars-cov-2 Virusmentioning
confidence: 99%
“…Instead, Wang et al identified a human defensin 5 (HD5), secreted by Paneth cells to bind (1) "Classical RAS ACE-Ang II-AT1 regulatory axis" and (2) "ACE2-Ang-(1-7)-Mas counter-regulatory axis." Abbreviations: (P) RR, (pro) renin receptor; Ang, angiotensin; ACE, angiotensinconverting enzyme; ACE2, angiotensin-converting enzyme 2; NEP, neutral endopeptidase; PEP, prolyl endopeptidase; PCP, prolyl carboxypeptidase [3]. B Structure of S CTD-human ACE2 Complex: The core subdomain and external subdomain in SARS-CoV-2-CTD are colored cyan and orange, respectively.…”
Section: Ace2: a Receptor Of Coronavirusesmentioning
confidence: 99%
“…The gradual respiratory failure observed leads to injuries, with the number of cells in monocytes, lymphocytes, leukocytes, cytokines, T cells, and biomarker-related infections changing in the serious cases (Wang et al 2020c). These infection strategies of COVID-19 are depended explicitly on their strains and genomic pattern (Torres et al 2021;Hasana et al 2021). However, it was quickly shown that COVID-19 also targets other organic systems, whether through overt viral infection or indirect immune response results.…”
Section: Introductionmentioning
confidence: 99%