Genetic factors affecting antibody responses to four species of nematode parasite in Romney ewe lambs

Serum antibody responses in pigs trickle-infected with Ascaris and Trichuris: Heritabilities and associations with parasitological findings

“…Antibodies for measuring IgE in swine serum are presently unavailable. Heritabilities for the serum levels of parasite specific antibodies in our study are in the same range as those found in sheep (Douch et al, 1995) and cattle (Morris et al, 2003) whereas Gasbarre et al (1993) reported estimates up to 0.99 in the same cattle breed. It is well established that hosts mount a T H 2-type immune response following infection with gastrointestinal nematodes (reviewed by Anthony et al, 2007).…”

Genetics of adaptation in domestic farm animals: A review

“…Gruner et al, 2004). Douch et al (1995), working with Romney ewes in New Zealand, studied the antibody levels against antigens from infective larvae of C. curtecei, H. contortus, O. circumcincta, or T. colubriformis and immunoglobulin G 1 (IgG 1 ) specific to C. curtecei or T. colubriformis and reported heritability values for antibody and IgG 1 ranging from 0.18 to 0.37 with average of 0.26 (for details, refer to the article). Heritabilities of log e (FEC + 100) and dag score (measure of breach soiling) were 0.28 and 0.13, respectively.…”

Sire effects on antibodies to nematode parasites in grazing dairy cows

“…The coefficients of variation for the L3 stages (0.18-0.24 in these data) can be compared with values of 0.30-0.38 obtained from antibodies to the (Douch et al 1995b). …”

“…These reflected important genetic differences, especially since they were consistent for the sires from herd to herd, and also across antibody types. In sheep, Douch et al (1995a,b) found that sire effects on antibody levels to nematodes showed significant heritabilities, and Douch et al (1995b) observed high genetic correlations (averaging 0.84) among the host levels of antibodies to four different nematode species in sheep. In beef calves, Gasbarre et al (1990) also found that host differences in FEC were reflected in worm-count differences in five different nematode species.…”