Genetic fine structure of the albino (<i>al</i>) region of<i>Neurospora crassa</i>

Subden, R. E.; Threlkeld, S. F. H.

doi:10.1017/s0016672300001476

Cited by 15 publications

(5 citation statements)

References 8 publications

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“…We have previously reported gene linkage studies (5), polar lipid analyses (6), and analyses of carotenoid (3) and steol intermediates (7) of some of these Neurospora strains.…”

Section: Introductionmentioning

confidence: 99%

The terpenyl pyrophosphates of wild type and tetraterpene mutants ofNeurospora crassa

Kushwaha

Kates

Renaud

et al. 1978

Lipids

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Mutations to two albino loci ofNeurospora (al‐2 andal‐3) are known to block tetraterpene synthesis prior to phytoene but after farnesyl pyrophosphate. Analysis of the terpenyl pyrophosphates labeled with [214C] mevalonic acid revealed the presence of radioactive prephytoene, pyrophosphate in both albino mutants and in the corresponding wild type strain. Theal‐2 andal‐3 mutations are thus associated with lesions between prephytoene pyrophosphate and phytoene.

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“…We have previously reported gene linkage studies (5), polar lipid analyses (6), and analyses of carotenoid (3) and steol intermediates (7) of some of these Neurospora strains.…”

Section: Introductionmentioning

confidence: 99%

The terpenyl pyrophosphates of wild type and tetraterpene mutants ofNeurospora crassa

Kushwaha

Kates

Renaud

et al. 1978

Lipids

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“…For complementation tests, see references 500, 1039, and 1041. Fine-structure mapping (500, 1042). Translocation T(4637), inseparable from al-i, was the first albino mutation and one of the first chromosome rearrangements in Neurospora to be identified and studied (656).…”

Section: Al: Albinomentioning

confidence: 99%

“…For complementation, see references 500 and 1041. Fine-structure mapping (500,1042) needs reevaluation because of new information on the location of the arg-6 marker (797). al-3: albino-3 VR.…”

Section: Al: Albinomentioning

confidence: 99%

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Chromosomal loci of Neurospora crassa

Perkins¹,

Radford²,

Newmeyer³

et al. 1982

Microbiol Rev

263

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I I ' ~~~~T h Ñ CiOr(r r N z ADDITIONAL LOCI IN LINKAGE GROUP ILinked to mt (8 to 12%) Linked to mt, acr-3 (5%) Right of arg-i (5/29) Linked to so and aro-8 Right of un-18 Between ad-5 and the centromere Between arg-i (4%) and his-3 (I to 2%) Between In(H4250) and T(39311) Left of mt (23%) Linked to mt (2%) and aza-i (39%o) Left of nit-2 (30%) Left of mt (14%) Linked to un-i (9%), probably to the right Linked to hom (1%), probably to the right Linked to mt (17 to 22%) Between T(NM103) and al-2 (18%) Between T(4540) and cr-2Between thi-i (12 to 20%/6) and ad-9 (5%) Linked to ad-5 (1/54), probably to the left Linked to mt (6%) Linked to cys-5 (<1%), probably to the right Right of ad-9 (12%), linked to al (0/76) Right of his-3 (2%) Between the T(AR173) breakpoints Linked to al-2 (10%) and nic-i (1 to 5%) Linked to ad-9 (0/44); right of thi-i (2%) Linked to mt (5%), probably to the left Linked to al-I (10%) Right of os-i (3%) Between nit,i (5 to 19%) and al-I (6 to 19%io) Linked near arg-i Left of al-2 (25%o) Left of mt (16%) Right of nic-2 (6%) Linked to ad-9 (2%), probably to the right Left of cr-i (15%) Left of mt (10%) Probably between his-2 (3%) and cr-i (3%) Between T(NM103) and the right tip Between mt (20%) and arg-i (1%) Between ad-3 (6%) and al-i (16%) Between his-3 and nic-2 Between cyh-i (5%) and al-I (7%) Linked to cyh-i (18%), al-i (2%), and mb-2 (6%) Between arg-i (3%) and T(39311) Between tre (41%) and ad-9 Linked to mt (9%) Linked to mt (20%) Complex phenotype. Alternative requirements: 2-acetylaminofluorine, certain azo dyes, or certain single amino acids. Cold sensitive. Originated among progeny of a rib-i strain that had become tolerant to 2-acetylaminofluorine.

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“…Old thalli of many moulds are rarely white, but pigmented with various substances, the more frequent being quinones or carotenoids (Valadon, 1966(Valadon, , 1976Thomson, 197 1 ;Neveu, 1974). The genetic control of carotenoid biosynthesis was elucidated through mutational analysis of producer micro-organisms accessible to genetical experimentation, like Neurospora crassa (Subden & Threlkeld, 1968, 1969, 1970Goldie & Subden, 1973;Harding & Turner, 1981) and Ustilago violacea (Garber etal., 1975;Cattrall et al, 1978;Garber & Owens, 1980;Garber et al, 1980;Garber, 1980;Tanabe & Garber, 1980). Data for quinone pigments are very sparse, probably because of the great variety of products and the lack of sexuality of many producers.…”

Section: Introductionmentioning

confidence: 99%

Genes Controlling Pigmentation in Nectria haematococca

Parisot¹,

Maugin²,

Gerlinger³

1984

Microbiology

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The Sl homothallic wild-type strain of Nectria haematococca produces grey-purplish colonies on PDA medium, due to synthesis of fusarubin and related naphthazarins. Seventeen yellow, beige or white mutants were isolated. On the basis of recombination tests they were divided into six distinct chromosomal regions. Four of them, designated befB, befC, belB and belC, may be regarded as regulatory genes which uncouple the processes of ageing and pigmentation that are normally associated in the wild-type. The two others, alyA and yelJ-beiW, control the biosynthesis of naphthazarins. Mutations in alyA were found epistatic to yelJ and beiW mutations, indicating that the aZyA locus acts on an earlier biosynthetic step than the yelJ-bei W region. The latter was shown to comprise two closely linked genes, yielding yellow or beige colours when mutated. Analysis of polar mutations suggests that they form a single unit of transcription. One of these two genes probably controls a late oxidation step in naphthazarin biosynthesis.

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Genetic fine structure of the albino (al) region ofNeurospora crassa

Cited by 15 publications

References 8 publications

The terpenyl pyrophosphates of wild type and tetraterpene mutants ofNeurospora crassa

The terpenyl pyrophosphates of wild type and tetraterpene mutants ofNeurospora crassa

Chromosomal loci of Neurospora crassa

Genes Controlling Pigmentation in Nectria haematococca

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