2023
DOI: 10.1111/iji.12622
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Genetic landscape of human platelet antigen variants in the Indian population analysed from 1029 whole genomes

Abstract: Genetic variants in human platelet antigens (HPAs) considered allo‐ or auto antigens are associated with various disorders, including neonatal alloimmune thrombocytopenia, platelet transfusion refractoriness and post‐transfusion purpura. Although global differences in genotype frequencies were observed, the distributions of HPA variants in the Indian population are largely unknown. This study aims to explore the landscape of HPA variants in India to provide a basis for risk assessment and management of related… Show more

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