2024
DOI: 10.1111/jcmm.70204
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Genetic landscape of Romanian PPGLs

Sofia‐Maria Lider‐Burciulescu,
Monica Gheorghiu,
Elena Braha
et al.

Abstract: Pheochromocytomas and paragangliomas (PPGLs) are rare neuroendocrine tumours that originate from chromaffin cells and occur in the adrenal medulla and in the sympathetic or parasympathetic ganglia. Nearly 70% of PPGLs result from germline or somatic mutations in a single driver gene. The aim of this study was to characterize the genetic background and clinical characteristics related to genetic profile of patients with PPGLs from Romania. We retrospectively retrieved data of 125 patients consecutively register… Show more

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