Genetic mapping of Uba3O.2.2, a pupal lethal mutation in Drosophila melanogaster

Mast, Elizabeth; Bieser, Kayla L; Abraham-Villa, Mary; Adams, Vanessa M.; Akinlehin, Akinwonuola J; Aquino, Lynarose Z; Austin, Joseph L.; Austin, A.; Beckham, Carissa N; Bengson, Ethan J; Bieszk, Amanda; Bogard, Brianna L; Brennan, Rosie; Brnot, Rebecca M; Cirone, Nicholas J; Clark, Matt; Cooper, B.; Cruz, Diana García; Daprizio, Katlyn A; DeBoe, Jason; Dencker, Michaela M; Donnelly, Laura; Driscoll, Leanne; DuBeau, Ryan J; D’Urso, S.; Ejub, Adam; Elgosbi, Waad; Estrada, Mario Pablo; Evins, Kaeli; Fox, Patricia G; France, John C.; Hernandez, M.; Garcia, Leandra Do Couto; Garl, Olivia; Gorsuch, Myeerah R; Gorzeman-Mohr, Mikayla A; Grothouse, Madison E; Gubbels, Marc‐Jan; Hakemiamjad, Romina; Harvey, C.; Hoeppner, Marc P.; Ivanov, Julian; Johnson, Victoria L.; Johnson, Jessica L; Johnson, Ashton; Johnston, Karen; Keller, Katie; Kennedy, Breandán N; Killian, Levi R; Klumb, Marissa; Koehn, Olivia J.; Koym, Aaron S; Kress, Kari J; Landis, Regan E; Lewis, Kaitlyn N.; Lim, Erna; López, Irma; Lowe, David; Carretero, Paula Luengo; Lunaburg, Grace; Mallinder, Samantha L; Marshall, Nicholas; Mathew, Jessica H.; Mathew, Jasmine; Mcmanaway, Hailee S; Meegan, Emily N; Meyst, Jacob D; Miller, Max J.; Minogue, Colin K; Mohr, Alina A; Moran, Chelsea; Moran, Anthony; Morris, Mark; Morrison, Michael D.; Moses, Eric K.; Mullins, Colleen R. Bronson; Neri, Claudia; Nichols, Jess M; Nickels, Bryce E.; Okai, Akosua M; Okonmah, Chiedu; Paramo, Makena; Paramo, Meagan; Parker, S.; Parmar, Neil K; Paschal, Jonathan W.; Patel, Prem; Patel, Dinesh G.; Perkins, Eugene H.; Perry, Mary Ellen; Perry, Zachary; Pollock, Andrew; Portalatin, Oxxyris; Proffitt, Kamron S; Queen, Jason T; Quemeneur, Alexis C; Richardson, Anna; Rosenberger, Kaylee; Rutherford, Anthony J.; Santos-Perez, Itchel X; Sarti, Cristina; Schouweiler, Lacey J; Sessing, Lauren M; Setaro, Sara O; Silvestri, Christopher F; Smith, Olivia A; Smith, M; Sumner, J.; Sutton, Rosemary; Sweckard, Lindsay; Talbott, Nicholas B; Traxler, Peyton A; Truesdell, J.; Valenti, Anna; Verace, Leif; Vijayakumar, Parameswaran; Wadley, William L; Walter, K.; Williams, Alan; Wilson, Theresa; Witbeck, Makayla A; Wobler, Trinity M; Wright, Lucas J; Zuczkowska, Karolina A; Devergne, Olivier; Hamill, Danielle R.; Shah, Hemin P; Siders, Jamie L; Taylor, Elizabeth E; Vrailas-Mortimer, Alysia D.; Kagey, Jacob D.

doi:10.17912/micropub.biology.000542

2022

DOI: 10.17912/micropub.biology.000542

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Genetic mapping of Uba3O.2.2, a pupal lethal mutation in Drosophila melanogaster

Elizabeth Mast

Kayla L Bieser

Mary Abraham-Villa

et al.

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Fly-CURE, a multi-institutional CURE using Drosophila , increases students' confidence, sense of belonging, and persistence in research

Merkle,

Devergne,

Kelly

et al. 2023

J Microbiol Biol Educ.

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The Fly-CURE is a genetics-focused multi-institutional Course-Based Undergraduate Research Experience (CURE) that provides undergraduate students with hands-on research experiences within a course. Through the Fly-CURE, undergraduate students at diverse types of higher education institutions across the United States map and characterize novel mutants isolated from a genetic screen in Drosophila melanogaster . To date, more than 20 mutants have been studied across 20 institutions, and our scientific data have led to eleven publications with more than 500 students as authors. To evaluate the impact of the Fly-CURE experience on students, we developed and validated assessment tools to identify students’ perceived research self-efficacy, sense of belonging in science, and intent to pursue additional research opportunities. Our data, collected over three academic years and involving 14 institutions and 480 students, show gains in these metrics after completion of the Fly-CURE across all student subgroups analyzed, including comparisons of gender, academic status, racial and ethnic groups, and parents’ educational background. Importantly, our data also show differential gains in the areas of self-efficacy and interest in seeking additional research opportunities between Fly-CURE students with and without prior research experience, illustrating the positive impact of research exposure (dosage) on student outcomes. Altogether, our data indicate that the Fly-CURE experience has a significant impact on students’ efficacy with research methods, sense of belonging to the scientific research community, and interest in pursuing additional research experiences.

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Fly-CURE, a multi-institutional CURE using Drosophila , increases students' confidence, sense of belonging, and persistence in research

Merkle,

Devergne,

Kelly

et al. 2023

J Microbiol Biol Educ.

Self Cite

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

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Genetic mapping of Uba3O.2.2, a pupal lethal mutation in Drosophila melanogaster

Cited by 1 publication

References 10 publications

Fly-CURE, a multi-institutional CURE using Drosophila , increases students' confidence, sense of belonging, and persistence in research

Fly-CURE, a multi-institutional CURE using Drosophila , increases students' confidence, sense of belonging, and persistence in research

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