Genetic Studies on Herpes Simplex Virus

Strain HF (type 1) produces large plaques with a single flat polykaryocyte, whereas strain KY (type 2) produces small ones with round cells. Four recombinants were obtained by cross of HF X KY which possessed the characters intermediate between the parents with respect to plaque size and cytopathogenic effect. Further crosses between these recombinants produced HF-type virus. The crosses between the one recombinant and fresh isolates or mutant viruses also produced HF-type virus at different ratios.

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Genetic Studies on Herpes Simplex Virus

Cited by 3 publications

References 5 publications

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Antigenic Studies on Type 2 Herpes Simplex Viruses by Neutralization Kinetics

Genetic Analysis of Polykaryocytosis by Herpes Simplex Virus

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