Genetic Toxicological Profile of Carbofuran and Pirimicarb Carbamic Insecticides

Vitamin C acts as a hepatoprotectant in carbofuran treated rat liver slices in vitro

“…The application of carbamates has been preferred over organophosphates and organochlorines as these compounds were extremely toxic and possessed delayed neurotoxic effects [1] , [2] . Organocarbamates share with organophosphates in their abilities to inhibit cholinesterases and therefore exhibit similar symptomatology during acute and chronic exposures [3] . Positive correlations have been reported between acetylcholine accumulation and oxidative stress [4] , [5] .…”