Genetic variability of type#$#nbsp;3 echoviruses

Molecular epidemiology of coxsackievirus type B1

“…The estimates of average evolutionary divergence of sequence pairs within genotypes varied from 0.08 % to 8.3 %, and between genotypes, from 12.1 % (between genotypes I and II) to 28.2 % (between genotypes I and V), which conformed to the generally accepted criterion for enterovirus genotype demarcation (less than 11 % nucleotide sequence variation in the VP1 region within an enterovirus genotype and more than 11 % nucleotide sequence variation in the same region between enterovirus genotypes) [22]. In the literature, different genotypes and clusters for echoviruses 3, 6, 11 and 30, coxsackievirus type B4 and B5 have been described [23][24][25][26][27][28][29].…”