Genetic variation of bioavailable iron and zinc in grain of a maize population

Šimić, Domagoj; Sudar, Rezica; Ledenčan, Tatjana; Jambrović, Antun; Zdunić, Zvonimir; Brkić, Ivan; Kovačević, Vlado

doi:10.1016/j.jcs.2009.06.014

Cited by 50 publications

(25 citation statements)

References 35 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Moreover, mineral concentrations (e.g., Cu, Fe, Mn, and Zn) in maize grain are relatively low when compared to animal food products (Wang et al 2003). The concentration even decreased in the past decades due to breeders selecting exclusively for grain yield but not grain quality (Fan et al 2008;Šimic et al 2009;Anandan et al 2011). Thus, since the concentration of these dietary minerals in maize grain is not sufficient to meet the dietary requirement of humans' daily intake when these foods are consumed in typical amounts, improving the mineral concentration in maize grain is of great interest.…”

Section: Introductionmentioning

confidence: 99%

Comprehensive phenotypic analysis and quantitative trait locus identification for grain mineral concentration, content, and yield in maize (Zea mays L.)

Chen

Liu

et al. 2015

Theor Appl Genet

View full text Add to dashboard Cite

Understanding the correlations of seven minerals for concentration, content and yield in maize grain, and exploring their genetic basis will help breeders to develop high grain quality maize. Biofortification by enhanced mineral accumulation in grain through genetic improvement is an efficient way to solve global nutrient malnutrition, in which one key step is to detect the underlying quantitative trait loci (QTL). Herein, a maize recombinant inbred population (RIL) was field grown to maturity across four environments (two locations × two years). Phenotypic data for grain mineral concentration, content and yield were determined for copper (Cu), iron (Fe), manganese (Mn), zinc (Zn), magnesium (Mg), potassium (K) and phosphorus (P). Significant effects of genotype, location and year were observed for all investigated traits. The strongest location effects were found for Zn accumulation traits probably due to distinct soil Zn availabilities across locations. Heritability (H (2)) of different traits varied with higher H (2) (72-85 %) for mineral concentration and content, and lower (48-63 %) for mineral yield. Significant positive correlations for grain concentration were revealed between several minerals. QTL analysis revealed 28, 25, and 12 QTL for mineral concentration, content and yield, respectively; and identified 8 stable QTL across at least two environments. All these QTL were assigned into 12 distinct QTL clusters. A cluster at chromosome Bin 6.07/6.08 contained 6 QTL for kernel weight, mineral concentration (Mg) and content (Zn, K, Mg, P). Another cluster at Bin 4.05/4.06 contained a stable QTL for Mn concentration, which were previously identified in other maize and rice RIL populations. These results highlighted the phenotypic and genetic performance of grain mineral accumulation, and revealed two promising chromosomal regions for genetic improvement of grain biofortification in maize.

show abstract

Section: Introductionmentioning

confidence: 99%

Comprehensive phenotypic analysis and quantitative trait locus identification for grain mineral concentration, content, and yield in maize (Zea mays L.)

Chen

Liu

et al. 2015

Theor Appl Genet

View full text Add to dashboard Cite

show abstract

“…The increment in starch contents of high-yielding maize genotypes may dilute Fe and Zn concentrations. Some other researchers (Menkir, 2008;Šimić et al, 2009;Lung'aho et al, 2011) observed no relationship between grain Fe, Zn, and maize yield, whereas Chakraborti et al (2009) found a positive correlation between Zn and maize yield but no correlation between grain Fe and maize yield. Brkić et al (2004) studied 121 maize genotypes and found no relationship between grain yield and Fe and suggested that this relationship is also dependent on the specific breeding material under consideration.…”

Section: Correlations Between Grain Iron and Zinc And Maize Yieldmentioning

confidence: 95%

“…Different researchers (Oikeh et al, 2003a, its ability to form insoluble particles that cannot pass through membrane transporters via enterocytes, resulting in minerals being unavailable to humans (Raboy, 2001;Gupta et al, 2015). Low-phytate strains are available in maize , but they have low seedling vigor (Bänziger and Long, 2000;Šimić et al, 2009). Tako et al (2016) reported that anionic effects of phytate are dosedependent and initiate at 2 to 10 mg per meal.…”

Section: Determination Of Iron and Zinc Bioavailabilitymentioning

confidence: 99%

“…Phytate binds with divalent cations, even in the alimentary canal, and inhibits bioavailability of these cations. Low-phytate strains are available in maize , but they have low seedling vigor (Bänziger and Long, 2000;Šimić et al, 2009). Phytate affects the germination efficiency and crop stand establishment; therefore, breeders usually do not focus on the decrease of phytic acid as a breeding objective (notwithstanding the presence of its natural variation in different crops) in their biofortification programs (Ortiz-Monasterio et al, 2007).…”

Section: Determination Of Iron and Zinc Bioavailabilitymentioning

confidence: 99%

See 1 more Smart Citation

Iron and Zinc in Maize in the Developing World: Deficiency, Availability, and Breeding

et al. 2018

View full text Add to dashboard Cite

Maize (Zea mays L.) is the third most important cereal in the world and the most important food security crop in sub‐Saharan Africa. Maize provides energy and micronutrients. Deficiencies of the essential micronutrients Zn and Fe are fifth and sixth ranked among the top 10 most important risk factors for conditions such as anemia, low cognitive functioning, and impaired immune system (Fe deficiency) and diarrhea, skin inflammation, and recurrent infections (Zn deficiency) in humans, affecting more than two billion people worldwide. Poverty, lack of access to balanced diets and awareness, and low phytoavailability and bioavailability of these nutrients are major reasons for deficiencies. Breeding for mineral‐rich maize is a sustainable and cost‐effective approach to reduce micronutrient deficiencies. Since 2004, there has been significant progress in improving maize for Zn content. The aim of this review was to capture recent developments, trends, and progress in maize Fe and Zn biofortification and to identify challenges and ways to overcome them. HarvestPlus has set target levels for Fe (60 μg g−1) and Zn (38 μg g−1) in maize. Zinc target levels have been reached, but conventional breeding alone cannot enhance Fe to the recommended levels. Techniques such as oligo‐directed mutagenesis, reverse breeding, RNA‐directed DNA methylation, and gene editing could be used in future to speed up maize Fe biofortification. Additional research is required on Fe and Zn bioavailability in maize products, and on interactions of Fe and Zn with Ca and phytate and their influence on absorption, to better understand the underlying mechanisms.

show abstract

“…The heterogeneous distributions of elements within the grain may to some extent also be related to their chelating ligands such as phytate and proteins (Hansen et al 2012). In cereal grain, most of Fe, Zn, and Ca are thought to be complexed mainly with P‐enriched PA, forming insoluble complexes (García‐Estepa et al 1999; Šimić et al 2009; Tavajjoh et al 2011). In a small portion of soluble extractions, recent studies showed that a substantial portion of Fe coeluted with P although Zn coeluted with sulfur‐containing ligands in the barley embryo (Persson et al 2009), Fe and Zn bound to nonprotein amino acid as nicotianamine (NA) and deoxymugineic acid (DMA) in rice endosperm (Lee et al 2009, 2011), and Fe bound to soluble phytate and NA/DMA in wheat flour (Eagling et al 2014).…”

mentioning

confidence: 99%

Nutritional Composition of Iron, Zinc, Calcium, and Phosphorus in Wheat Grain Milling Fractions as Affected by Fertilizer Nitrogen Supply

et al. 2016

View full text Add to dashboard Cite

Fe and Zn deficiencies are global nutritional problems. N supply could increase Fe and Zn concentrations in wheat grain. This study was conducted to determine the impacts of different N rates (0, 122, 174, and 300 kg/ha) on the distribution and speciation of Fe and Zn in wheat grain milling fractions under field conditions. Zn and protein concentrations were increased, whereas Fe was less affected in the flour fractions with increasing N rates. Further analysis with size‐exclusion chromatography coupled with inductively coupled plasma mass spectrometry revealed that Fe and Zn bound to low‐molecular‐weight (LMW) compounds in the flour fractions (probably Fe‐nicotianamine [NA], Fe‐deoxymugineic acid, or Zn‐NA) were less affected by increasing N supply, representing 3.5–10.9% of total Fe and 2.5–56.6% of total Zn. In the shorts fraction, LMW‐Fe was absent, and LMW‐Zn with higher N supply was over twice as high as that in control and 3–27 times as high as that in the other milling fractions. In the flour fractions, the molar ratios of phytic acid (PA)/Fe and PA/Zn (both less than 30.5) decreased, whereas soluble LMW‐Fe/Zn was not affected with increasing N rates.

show abstract

Genetic variation of bioavailable iron and zinc in grain of a maize population

Cited by 50 publications

References 35 publications

Comprehensive phenotypic analysis and quantitative trait locus identification for grain mineral concentration, content, and yield in maize (Zea mays L.)

Comprehensive phenotypic analysis and quantitative trait locus identification for grain mineral concentration, content, and yield in maize (Zea mays L.)

Iron and Zinc in Maize in the Developing World: Deficiency, Availability, and Breeding

Nutritional Composition of Iron, Zinc, Calcium, and Phosphorus in Wheat Grain Milling Fractions as Affected by Fertilizer Nitrogen Supply

Contact Info

Product

Resources

About