Genetically modified insects as a public health tool: discussing the different bio-objectification within genetic strategies

Reis‐Castro, Luísa

doi:10.3325/cmj.2012.53.635

Cited by 12 publications

(13 citation statements)

References 11 publications

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“…Multiple traditional measures and strategies have been employed for dengue prevention and control, but most of these are compliance‐ and community involvement–dependent strategies which are hindered by poor compliance and absence of active local community involvement . Modern, integrated vector management approaches using novel biological control approaches such as paratransgenesis, sterile insect techniques, and production of genetically modified vectors, are urgently needed as well as innovative vaccine candidates. Our data presented in this study may be important for dengue vaccine development, particularly with regard to future vaccine composition.…”

Section: Discussionmentioning

confidence: 99%

Dengue viruses circulating in Indonesia: A systematic review and phylogenetic analysis of data from five decades

Harapan

Michie

Yohan

et al. 2019

Reviews in Medical Virology

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Although epidemiological and molecular epidemiological (serotype, genotype, and lineage information) data are available for several major cities in Indonesia, there is yet to be a comprehensive national study of dengue in Indonesia over time. This study was conducted to provide a comprehensive epidemiology of circulating dengue viruses (DENV) in Indonesia between 1973 and 2016. This was conducted through a systematic review of the literature and phylogenetic analysis of available DENV sequences. Available data from National Disease Surveillance System have indicated an increasing trend of dengue incidence in Indonesia over the past 50 years. Incidence rates appear to be cyclic, peaking approximately every 6 to 8 years. In contrast, the case fatality rate has decreased approximately by half with each decade since 1980.Over this 50-year time span, serotype shifts, genotype displacement within DENV-1 and DENV-2, and introduction of DENV-1 and DENV-3 genotype from other countries occurred. These events were associated with increased incidence of dengue cases. Our study also provides a valuable national snapshot of DENV genetic diversity in Indonesia that may contribute to development of more effective dengue vaccine compositions for the region.

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Section: Discussionmentioning

confidence: 99%

Dengue viruses circulating in Indonesia: A systematic review and phylogenetic analysis of data from five decades

Harapan

Michie

Yohan

et al. 2019

Reviews in Medical Virology

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“…Other chemical control strategies, such as insecticide-treated windows, door screens or curtains, insecticide or larvicide-treated water container covers and insecticide-treated bed nets, have varied impacts on vector abundance as measured by the container index (CI) and Breteau index (BI) [245]. In recent years, modern, integrated vector management approaches using novel biological control approaches such as paratransgenesis [246][247][248][249][250][251][252][253][254], sterile insect techniques [246,247,255] and the production of genetically modified vectors [246,247,[256][257][258] have been also developed.…”

Section: Vector Control and Preventionmentioning

confidence: 99%

Dengue: A Minireview

Harapan

Michie

Sasmono

et al. 2020

Viruses

241

228

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Dengue, caused by infection of any of four dengue virus serotypes (DENV-1 to DENV-4), is a mosquito-borne disease of major public health concern associated with significant morbidity, mortality, and economic cost, particularly in developing countries. Dengue incidence has increased 30-fold in the last 50 years and over 50% of the world’s population, in more than 100 countries, live in areas at risk of DENV infection. We reviews DENV biology, epidemiology, transmission dynamics including circulating serotypes and genotypes, the immune response, the pathogenesis of the disease as well as updated diagnostic methods, treatments, vector control and vaccine developments.

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“…In Recife, a massive trap intervention was implemented for two years with population suppression of about 90% [ 92 ]. Sterile [ 93 ], transgenic mosquitoes [ 94 ] and mosquitoes bearing Wolbachia [ 95 , 96 ] are being released under field-controlled conditions to better evaluate their impact on local vector populations and arbovirus transmission. There are promising results regarding transgenic mosquitoes, with sustained release reducing field populations of Ae.…”

Section: Control and Prevention Strategiesmentioning

confidence: 99%

The Zika Virus Epidemic in Brazil: From Discovery to Future Implications

Lowe

Barcellos

Brasil

et al. 2018

IJERPH

300

230

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The first confirmed case of Zika virus infection in the Americas was reported in Northeast Brazil in May 2015, although phylogenetic studies indicate virus introduction as early as 2013. Zika rapidly spread across Brazil and to more than 50 other countries and territories on the American continent. The Aedes aegypti mosquito is thought to be the principal vector responsible for the widespread transmission of the virus. However, sexual transmission has also been reported. The explosively emerging epidemic has had diverse impacts on population health, coinciding with cases of Guillain–Barré Syndrome and an unexpected epidemic of newborns with microcephaly and other neurological impairments. This led to Brazil declaring a national public health emergency in November 2015, followed by a similar decision by the World Health Organization three months later. While dengue virus serotypes took several decades to spread across Brazil, the Zika virus epidemic diffused within months, extending beyond the area of permanent dengue transmission, which is bound by a climatic barrier in the south and low population density areas in the north. This rapid spread was probably due to a combination of factors, including a massive susceptible population, climatic conditions conducive for the mosquito vector, alternative non-vector transmission, and a highly mobile population. The epidemic has since subsided, but many unanswered questions remain. In this article, we provide an overview of the discovery of Zika virus in Brazil, including its emergence and spread, epidemiological surveillance, vector and non-vector transmission routes, clinical complications, and socio-economic impacts. We discuss gaps in the knowledge and the challenges ahead to anticipate, prevent, and control emerging and re-emerging epidemics of arboviruses in Brazil and worldwide.

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Genetically modified insects as a public health tool: discussing the different bio-objectification within genetic strategies

Cited by 12 publications

References 11 publications

Dengue viruses circulating in Indonesia: A systematic review and phylogenetic analysis of data from five decades

Dengue viruses circulating in Indonesia: A systematic review and phylogenetic analysis of data from five decades

Dengue: A Minireview

The Zika Virus Epidemic in Brazil: From Discovery to Future Implications

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