Genetics and Immunology of Sex-Linked Antigens

Gasser, David L.; Silvers, Willys K.

doi:10.1016/s0065-2776(08)60686-0

Cited by 123 publications

(46 citation statements)

References 124 publications

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“…In contrast, M -> M, F -* F and F -* M grafts always succeeded. These ob- servations on skin engraftment were subsequently confirmed and extended by others (14)(15)(16)(17)(18)(19)(20). In addition, Lengerova and Chutna in 1959 carried out marrow grafts after 900 R total body irradiation in C57B1 mice and found that survival of males given female grafts was inferior to that of all other combinations (21).…”

Section: Introductionmentioning

confidence: 57%

Treatment of aplastic anemia by marrow transplantation from HLA identical siblings. Prognostic factors associated with graft versus host disease and survival.

Storb¹,

Prentice²,

Ed³

1977

J. Clin. Invest.

110

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Section: Introductionmentioning

confidence: 57%

Treatment of aplastic anemia by marrow transplantation from HLA identical siblings. Prognostic factors associated with graft versus host disease and survival.

Storb¹,

Prentice²,

Ed³

1977

J. Clin. Invest.

110

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“…This highly conserved antigen, which has been reviewed in great detail by Glasser and Silvers [4], has been hypothesized as being the essential inducer of testis differentiation in mammals. Mittwoch [12] has suggested that H-Y antigen exerts its effects on testis development by being responsible for the enhanced growth of the dominant heterogametic gonad at its critical stage of differentiation.…”

Section: Discussionmentioning

confidence: 99%

Effects of Type of Placentation on Birthweight and its Variability in Monozygotic and Dizygotic Twins

Corey

Nance

Kang

et al. 1979

Acta genet. med. gemellol.: twin res.

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Birthweight was measured on 188 monochorionic monozygotic, 54 dichorionic monozygotic, 102 like-sexed dizygotic, and 94 unlike-sexed dizygotic liveborn twin pairs. Overall, males were found to be significantly heavier than females. These differences were not significant, however, when birthweights were compared within zygosity/chorion-type categories. Males were also characterized by a slightly greater overall total variance. Comparisons of intrapair variation of monochorionic and dichorionic monozygotic twins revealed significant differences between monochorionic pairs and dichorionic separate pairs and no significant differences between monochorionic pairs and dichorionic fused pairs. The results of this study suggest that placental proximity may have as important an influence on variation in birthweight as does the presence or absence of vascular anastomoses.Key words: Birthweight, Twin pregnancy, Placental effects, Length of gestation, Sex effects, Fetal hormones Variation in human birthweight is known to be influenced by such factors as length of gestation [ 3 , 6 ] , race [ 1 ] , sex [17], parity [9] and maternal smoking history [11]. In addition, "maternal factors" are recognized to have powerful and possibly overriding effects on the expression of this trait [10,13], but the relative importance of fetal genoThis is paper No.

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“…Adsorption of alloantiserum aX2 Cells of three mouse strains, DBA/2, BALB/c, and A/J were positive with serum aX2. To investigate whether these strains (15,16). The occurrence of X-chromosome-linked recessive immune deficiency and X-linked autoimmune diseases in man also suggests an association between immunity'and genes on the X-chromosomes (17)(18)(19)(20).…”

Section: Resultsmentioning

confidence: 99%

Lymphocytes alloantigens associated with X-chromosome-linked immune response genes.

Zeicher¹,

Mozes²,

Lonai³

1977

Proc. Natl. Acad. Sci. U.S.A.

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A new polymorphic alloantigen system controlled by loci on the X-chromosome has been identified by using antisera from F1 hybrid mice differing in their X-chromosome. These alloantigens are associated with the X-linked immune response genes controlling the immune response to the so-called "thymus independent antigens" such as type III pneumococcal polysaccharide, poly(I)poly(C), and denatured DNA. They also show association with the histocompatibility locus present on the X-chromosome. They were mainly detected on a not yet characterized thymus-derived lymphocyte subpopulation. A certain similarity with the major histocompatibility complex of the mouse supports the possibility of additional I-like regions besides the I region of the histocompatibility-2 complex.

show abstract

Genetics and Immunology of Sex-Linked Antigens

Cited by 123 publications

References 124 publications

Treatment of aplastic anemia by marrow transplantation from HLA identical siblings. Prognostic factors associated with graft versus host disease and survival.

Treatment of aplastic anemia by marrow transplantation from HLA identical siblings. Prognostic factors associated with graft versus host disease and survival.

Effects of Type of Placentation on Birthweight and its Variability in Monozygotic and Dizygotic Twins

Lymphocytes alloantigens associated with X-chromosome-linked immune response genes.

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