Genetics and Luteinizing Hormone Receptors

Effects of Growth Hormone Review on Male Reproductive Functions

“…The levels of LH receptors in the testes of bGH transgenic mice are either normal or elevated, depending on the level of transgene expression (Amador et al, 1994). Interestingly, LH receptors in the testes of bGH transgenic mice are resistant to homologous downregulation, and the doses of hCG sufficient to reduce LH (hCG) binding in normal mice cause an increase in LH binding in these transgenic animals (Amador et al, 1994).…”