Genetics of pigmentation in skin cancer — A review

Antibacterial activity of Lawsonia inermis Linn (Henna) against Pseudomonas aeruginosa

“…They are ubiquitous in nature and are characteristically highly active. These compounds, being coloured, are responsible for the browning reaction in cut or injured fruits and vegetables and are an intermediate in the melanin synthesis pathway in human skin [18] . It is the presence of quinones in henna that gives the material its dyeing properties [3] .…”

“…Plates were kept for 2 h in refrigerator to enable prediffusion of the extracts into the agar. Then, the plates were incubated overnight (18 h) at 37 曟 . Ampicillin, gentamicin and amphotericin B were used as positive control.…”

Antimicrobial and Photometric assessment of Lawsonia inermis on Oral Bacteria and Tooth Colour

“…They are ubiquitous in nature and are characteristically highly active. These compounds, being colored are responsible for the coloring reaction in cut or injured fruits and vegetables and are an intermediate in the melanin synthesis pathway in human skin [16] . It is the presence of quinones in henna that gives the material its dyeing properties [17] .…”

Antioxidant Defense and UV-Induced Melanogenesis: Implications for Melanoma Prevention

“…When eumelanin present in almost every type of human skin serves as a UV filter and ROS scavenger to neutralize the toxic intermediates, pheomelanin prevalent in fair-skinned individuals with red hair has been shown to be a photosensitizer aggravating ROS formation after UVR (Takeuchi et al, 2004). Melanocytes produce varying ratios of eumelanin or pheomelanin that affect skin colors in different human populations and also have an influence involving the interplay between genetic factors and UV exposure on susceptibility to melanomagenesis (Scherer & Kumar, 2010). The possible contribution of oxidative stress to the development of melanoma involve several mechanisms and probably associates with melanogenesis since pheomelanin and eumelanin could lead to photogeneration of ROS and serve as a potential source of H 2 O 2 (Nofsinger et al, 2002).…”