Geniposide Causes Idiopathic Mesenteric Phlebosclerosis

Chuah, Yoen Young; Lee, Yeong Yeh

doi:10.5152/tjg.2023.23208

Turk J Gastroenterol 2023

DOI: 10.5152/tjg.2023.23208

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Geniposide Causes Idiopathic Mesenteric Phlebosclerosis

Yoen Young Chuah

Yeong Yeh Lee

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2024

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Idiopathic mesenteric phlebosclerosis missed by a radiologist at initial diagnosis: A case report

Wang,

Wan,

Liao

et al. 2024

World J Clin Cases

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BACKGROUND Idiopathic mesenteric phlebosclerosis (IMP) is a rare type of ischemic colitis characterized by thickening of the wall of the right hemicolon and calcification, sclerosis, and fibrosis of mesenteric veins. The diagnosis of IMP is based on typical clinical features and imaging findings. We report a case of IMP that was initially missed by the radiologist. CASE SUMMARY A 77-year-old woman was admitted to the hospital due to chronic diarrhea for over 2 months. She had been consuming Chinese patent medicines (CPM) containing fructus gardeniae for more than 15 years. Colonoscopy revealed an edematous mucosa, bluish-purple discoloration, erosions, and ulcerations throughout the colorectal area. Abdominal computed tomography (CT) showed diffuse mural thickening of the entire colorectum, with tortuous thread-like calcifications in the right hemicolon, left hemicolon, and rectum. Most of the calcifications were located in the mesenteric vein. The diagnosis of IMP was established based on medical history, colonoscopy, CT findings, and histopathological examination. The patient was treated conservatively with papaverine and rifaximin, and CPM was stopped. Her diarrhea symptoms improved, indicating the effectiveness of the treatment. Over the next several years, she took opium alkaloids for an extended period and did not require hospitalization for the aforementioned gastrointestinal disorder. CONCLUSION IMP is a rare gastrointestinal disease affecting Asian populations, possibly related to long-term herbal medicine intake. Accurate imaging analysis is crucial for diagnosis, but insufficient understanding of the disease can lead to misdiagnosis or missed diagnosis. Treatment strategies should be personalized.

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Idiopathic mesenteric phlebosclerosis missed by a radiologist at initial diagnosis: A case report

Wang,

Wan,

Liao

et al. 2024

World J Clin Cases

View full text Add to dashboard Cite

show abstract

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Geniposide Causes Idiopathic Mesenteric Phlebosclerosis

Cited by 1 publication

References 3 publications

Idiopathic mesenteric phlebosclerosis missed by a radiologist at initial diagnosis: A case report

Idiopathic mesenteric phlebosclerosis missed by a radiologist at initial diagnosis: A case report

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