Genital and lingual warts in small cetaceans from coastal Peru

Bressem, M.-F. Van; Waerebeek, Koen Van; Piérard, G. E.; Desaintes, Christian

doi:10.3354/dao026001

Cited by 36 publications

(24 citation statements)

References 12 publications

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“…Other inflammatory, infectious, or neoplastic diseases can at this stage not be ruled out. Though genital, cutaneous and oral papillomas (localized epithelium hyperplasia with a defined boundary and an intact basement membrane; Shah & Howley 1990) have been frequently described in odontocetes (Ge raci et al 1987, Lambertsen et al 1987, Bossart et al 1996, Van Bressem et al 1996, 1999, 2007b, Reh tanz et al 2006, Gottschling et al 2011, to the best of our knowledge, there are no published papers on cutaneous fibropapillomas in these marine mammals. Often caused by viruses in the family Papillomaviridae, fibropapillomas are commonly diagnosed on the skin of many terrestrial mammals including deer, camels, horses and zebras 1 where they can be plentiful and reach large sizes (Shope et al 1958, Sundberg & Nielsen 1981, Schulman et al 2003, Nel et al 2006.…”

Section: Malaysiamentioning

confidence: 97%

Cutaneous nodules in Irrawaddy dolphins: an emerging disease in vulnerable populations

Bressem¹,

Minton²,

Sutaria³

et al. 2014

Dis. Aquat. Org.

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The presence of cutaneous nodules is reported in vulnerable populations of Irrawaddy dolphins Orcaella brevirostris from Malaysia (Kuching, Bintulu-Similajau, KinabatanganSegama and Penang Island), India (Chilika Lagoon) and Bangladesh (Sundarbans). Approximately 5700 images taken for photo-identification studies in 2004 to 2013 were examined for skin disorders. Nodules were detected in 6 populations. They appeared as circumscribed elevations of the skin and varied in size from 2 to > 30 mm, were sparse or numerous and occurred on all visible body areas. In 8 photo-identified (PI) dolphins from India and Malaysia, the lesions remained stable (N = 2) or progressed (N = 6) over months but did not regress. The 2 most severely affected individuals were seen in Kuching and the Chilika Lagoon. Their fate is unknown. Cutaneous nodules were sampled in a female that died in a gillnet in Kuching in 2012. Histologically, the lesions consisted of thick collagen bundles covered by a moderately hyperplasic epithelium and were diagnosed as fibropapillomas. Whether the nodules observed in the other O. brevirostris were also fibropapillomas remains to be investigated. Disease prevalence ranged from 2.2% (N = 46; Bintulu-Similajau) to 13.9% (N = 72; Chilika) in 4 populations from Malaysia and India. It was not significantly different in 3 study areas in eastern Malaysia. In Chilika, prevalence was significantly higher (p = 0. well et al. 1975, Kiszka et al. 2009, Reif et al. 2009, Van Bressem et al. 2009b. In some small communities of inshore and estuarine populations, these pathologies are highly prevalent, may progress to cover extensive body areas and have been associated with the death or disappearance of severely affected individuals, including calves (Simões-Lopes et al. 1993, Van Bressem et al. 2007a, Kiszka et al. 2009, Daura-Jorge & Simões-Lopes 2011. However, their impact on the long-term viability of affected communities is still vastly unknown. The fungi Lacazia loboi, Fusarium spp., Paracoccidioides brasiliensis and Trichophyton spp. have been identified as the aetiological agents of some nodular disorders (Caldwell et al. 1975, Frasca et al. 1996, Van Bressem et al. 2007a, Esperón et al. 2012, Tanaka et al. 2012). Immune dysfunction is also known to play a role in the pathogenesis of L. loboi disease in coastal common bottlenose dolphins Tursiops truncatus from Florida, USA (Reif et al. 2009, Murdoch et al. 2010.Irrawaddy dolphins Orcaella brevirostris occur in large rivers and marine appended lakes in South Asia, as well as in the coastal waters of the Indo-Pacific Ocean (Smith 2009). Estuarine and nearshore populations are distributed in tropical and subtropical waters of the Indo-Pacific Ocean, from eastern India to the Philippines (Dolar et al. 2002, Minton et al. 2011. Riverine populations have been documented in 3 major river systems: the Mahakam (Indonesia), the Ayeyarwady (Myanmar) and the Mekong (Laos, Cambodia and Vietnam) (Smith 2009). Their habitat preference exposes them to multiple anthropog...

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Section: Malaysiamentioning

confidence: 97%

Cutaneous nodules in Irrawaddy dolphins: an emerging disease in vulnerable populations

Bressem¹,

Minton²,

Sutaria³

et al. 2014

Dis. Aquat. Org.

Self Cite

View full text Add to dashboard Cite

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“…Except for the harbor porpoise (Phocoena phocoena), molecular diagnosis was performed on all those cases, and the corresponding sequences are available in GenBank. Genital lesions of similar gross appearance have been associated with papillomaviruses in several cetacean species (Van Bressem et al 1996, 2007Gottschling et al 2011;Rehtanz et al 2012), so additional immunohistochemical and molecular studies are needed to identify the causative agent.…”

Section: Introductionmentioning

confidence: 99%

HERPESVIRUS-ASSOCIATED GENITAL LESIONS IN A STRANDED STRIPED DOLPHIN (STENELLA COERULEOALBA) IN THE CANARY ISLANDS, SPAIN

Sierra

Díaz‐Delgado

Arbelo

et al. 2015

Journal of Wildlife Diseases

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ABSTRACT:An adult male striped dolphin (Stenella coeruleoalba) stranded alive at Arico, Tenerife, Canary Islands, Spain. The dolphin died shortly after stranding, and a complete postmortem examination was performed. The most remarkable gross findings were two fleshy masses of approximately 1 cm diameter, near the tip of the penis. These masses were composed of hyperplastic epithelial cells with pigmentary incontinence. Ballooning degeneration and margination of chromatin was observed within the stratum corneum of the epidermis. A universal nested PCR assay that amplifies a conserved region within the polymerase gene of Herpesviridae was positive. The sequenced product was most closely related to a gammaherpesvirus that shared nucleotide identities of 93% with penile lesions from Atlantic and Mediterranean bottlenose dolphins (Tursiops truncatus). This similarity supports the hypothesis of sexual transmission between species.

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“…These cases were part of a sexually transmitted epidemic that involved adult male and female dolphins at both sites . Papillomavirusassociated orogenital papillomas have been described in other marine mammal species (Van Bressem et al 1996, 2007a, Bossart et al 2002, Ghim et al 2014). In our earlier study from 2003 to 2005, orogenital papillomas were described for the first time in association with virions ultrastructurally suggestive of a herpesvirus (Bossart et al 2005), and later with infection associated with the first reported American dolphin papillomavirus (Rehtanz et al 2006(Rehtanz et al , 2010.…”

Section: Discussionmentioning

confidence: 99%

Mucocutaneous lesions in free-ranging Atlantic bottlenose dolphins Tursiops truncatus from the southeastern USA

Bossart¹,

Schaefer²,

McCulloch³

et al. 2015

Dis. Aquat. Org.

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Mucocutaneous lesions were biopsied from free-ranging Atlantic bottlenose dolphins Tursiops truncatus inhabiting the Indian River Lagoon (IRL), Florida, and estuarine waters of Charleston (CHS), South Carolina, USA, between 2003 and 2013. A total of 78 incisional biopsies from 58 dolphins (n = 43 IRL, n = 15 CHS) were examined. Thirteen dolphins had 2 lesions biopsied at the same examination, and 6 dolphins were re-examined and re-biopsied at time intervals varying from 1 to 8 yr. Biopsy sites included the skin (n = 47), tongue (n = 2), and genital mucosa (n = 29). Pathologic diagnoses were: orogenital sessile papilloma (39.7%), cutaneous lobomycosis (16.7%), tattoo skin disease (TSD; 15.4%), nonspecific chronic to chronic-active dermatitis (15.4%), and epidermal hyperplasia (12.8%). Pathologic diagnoses from dolphins with 2 lesions were predominately orogenital sessile papillomas (n = 9) with nonspecific chronic to chronic-active dermatitis (n = 4), TSD (n = 3), lobomycosis (n = 1), and epidermal hyperplasia (n = 1). Persistent pathologic diagnoses from the same dolphins re-examined and re-biopsied at different times included genital sessile papillomas (n = 3), lobomycosis (n = 2), and nonspecific dermatitis (n = 2). This is the first study documenting the various types, combined prevalence, and progression of mucocutaneous lesions in dolphins from the southeastern USA. The data support other published findings describing the health patterns in dolphins from these geographic regions. Potential health impacts related to the observed suite of lesions are important for the IRL and CHS dolphin populations, since previous studies have indicated that both populations are affected by complex infectious diseases often associated with immunologic disturbances and anthropogenic contaminants.

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Genital and lingual warts in small cetaceans from coastal Peru

Cited by 36 publications

References 12 publications

Cutaneous nodules in Irrawaddy dolphins: an emerging disease in vulnerable populations

Cutaneous nodules in Irrawaddy dolphins: an emerging disease in vulnerable populations

HERPESVIRUS-ASSOCIATED GENITAL LESIONS IN A STRANDED STRIPED DOLPHIN (STENELLA COERULEOALBA) IN THE CANARY ISLANDS, SPAIN

Mucocutaneous lesions in free-ranging Atlantic bottlenose dolphins Tursiops truncatus from the southeastern USA

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