Genital Folliculosebaceous Cystic Hamartoma: A Case Report and Concise Review of the Literature

Abstract

Folliculosebaceous cystic hamartoma (FSCH) is an uncommon hamartoma that usually presents on the central face area of adults as an asymptomatic, solitary dome-shaped or pedunculated papule. We report a case of a 35-year-old female who presented with six-months history of skin lesions on her labia majora. Histological findings included cystically dilated hair follicles with branching epithelial strands and interconnecting sebaceous gland consistent with the diagnosis of FSCH. The genital variant of FSCH was first described in 1998 and since then only six cases have been reported in the literature. We aim to increase awareness of this rare presentation due to the significant psychological implications and the risk of misdiagnosis.

Giant Folliculosebaceous Cystic Hamartoma of the Face

“…In summary of the represented cases up to the present date, the typical clinical presentation of FSCH appears in the form of solitary, unilateral, skin-colored, protruding/pedunculated benign papules or nodules, which occur commonly on the face, especially on the nose [ 8 , 21 , 27 , 32 ]. Outside of facial predilection, other cases have already been described on the auricle and scalp [ 24 , 33 , 34 , 35 ], lower extremity [ 36 ], genital [ 11 , 37 , 38 ], nipple [ 16 , 39 , 40 ], upper lip and labial mucosa [ 41 ], and back [ 42 ]. Our case illustrates the constantly growing nature of FSCH, as evidenced by the advanced age of our patient at the initial diagnosis.…”