Genital Hailey- Hailey disease: a case repor

Thapa, Deeptara Pathak; Jha, Anil Kumar; Pudasaini, S; Kharel, Chandani; Shrestha, Shristi

doi:10.7241/ourd.20131.18

Cited by 2 publications

(3 citation statements)

References 12 publications

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“…Although mucosal involvement is not common, oral, esophageal, vulvar and conjunctival involvement can occur. 10,11 Longitudinal white lines on the fingernails and fine palmer pits are observed. Atypical variants are hyperkeratotic, verrucous, lichenified, papular, papulovesicular and vesiculopustular forms.…”

Section: Discussionmentioning

confidence: 98%

Hailey Hailey disease-a rare case report

et al. 2016

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Hailey-Hailey disease is an autosomal dominant acantholytic disorder relatively uncommon in India. It is characterized by painful, pruritic, foul smelling vesicles and bullous lesions with erosions in intertriginous areas such as the neck, axillae, inframammary areas and groin. The defect in ATPC2 gene leads to calcium channel dysfunction which results in defect in epidermis. Fungal infection, intertrigo, psoriasis, extramammary Paget's disease, acanthosis nigricans, pemphigus vegetans and Darier's disease are some of the dermatosis from which it needs to be differentiated. Histopathology has a key role in diagnosis of Hailey-Hailey disease with characteristic ‘dilapidated brick wall' appearance. Hailey-Hailey disease can be easily misdiagnosed by general physicians due to lack of knowledge of this uncommon disease as it resembles dermatosis involving intertriginous areas. Due to its relapsing and remitting course there is a need to have effective treatment options. We report a case of 45 year old middle aged female who presented with on and off itchy papules & vesicles over right inframammmary region around the umbilicus & medial aspect of right thigh. Skin biopsy revealed a diagnosis of Hailey-Hailey disease. This case is being reported due to its rare occurrence.

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Section: Discussionmentioning

confidence: 98%

Hailey Hailey disease-a rare case report

et al. 2016

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“…Among the eczematous conditions asteatotic dermatitis (20%) was most common followed by seborrheic dermatitis (15%). Thapa et al 10 where eczema (35.8%) was most common and in Khawar et al 11 eczema (40%).was after scabies, fungal infections were dominant (13.6%) in both age groups. Similar to Thapa et al 10 pruritus, dermatitis, eczema and bacterial infections were statistically significant (p<0.05) among three groups.…”

Section: Resultsmentioning

confidence: 91%

“…Thapa et al 10 where eczema (35.8%) was most common and in Khawar et al 11 eczema (40%).was after scabies, fungal infections were dominant (13.6%) in both age groups. Similar to Thapa et al 10 pruritus, dermatitis, eczema and bacterial infections were statistically significant (p<0.05) among three groups. Kalar et al 2 shown that in the < 60 years of age group, the frequency of diseases in decreasing order was found as follows: scabies (15.5%), fungal infections 13.6%, eczema 6.4%, pruritus 5.9%, bacterial infections and contact dermatitis 5.5%, psoriasis 5%.…”

Section: Resultsmentioning

confidence: 91%

Determination of the Prevalence of the Common Dermatological Conditions in Elderly Population Attending a Tertiary Care Hospital

Rahman

Mannan

Hossain³

et al. 2019

Med. Today

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Introduction: Skin disorders are common in elderly people. Systemic diseases promote the development of dermatological conditions. Various systemic diseases contribute to the presence of cutaneous disorders, indicating the possibility that a skin abnormality may sometimes be the first and only symptom of a much more serious medical problem. The aim of the study to determine the frequency of skin diseases in elderly patients. Materials & Methods: This was a cross-sectional study and non-probability convenient sampling technique was used. Patients were recruited from attending the Dermatology Out-patient Department of SZMCH during the study from January’2018 to July’2018. Patients included in the study having skin diseases aged between 60-80 years, including all those who were diabetic and hypertensive because diabetes and hypertension are the most common comorbid conditions among these elderly patients. Patients were included having skin diseases including pruritus, dermatitis, xerosis, eczema, psoriasis, scabies, bacterial infection, and fungal infections. Results: More than half (53.0%) patients belonged to age 71-80 years. Three fourth (75.0%) patients had pruritus followed by 37(37.0%) had dermatitis, 24(24.0%) had xerosis, 23(23.0%) had eczema and 12(12.0%) had bacterial infections. Pruritis, dermatitis, eczema and bacterial infections were statistically significant (p<0.05) among three groups. Conclusion: More than half of the patients belonged to age more than 70 years of age. Most common (three fourth) skin patients had pruritis, followed by more common skin patients were found dermatitis, xerosis, eczema and bacterial infection. Pruritis, dermatitis, eczema and bacterial infections were statistically significant in different age groups. Medicine Today 2019 Vol.31(2): 98-101

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Genital Hailey- Hailey disease: a case repor

Cited by 2 publications

References 12 publications

Hailey Hailey disease-a rare case report

Hailey Hailey disease-a rare case report

Determination of the Prevalence of the Common Dermatological Conditions in Elderly Population Attending a Tertiary Care Hospital

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