Genital herpes: an increasing problem?

Hindley, D J; Adler, M W

doi:10.1136/sti.61.1.56

Cited by 8 publications

(4 citation statements)

References 5 publications

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“…The incidence of HSV-2 infection was estimated from age stratified seroprevalence data.' [3][4][5][6][7][8][9][10][11][12][13][14][15] Using standard survival time theory,'6 the proportion seronegative at exact age a, S(a), was defined in terms of the force of infection k(a):…”

Section: Methodsmentioning

confidence: 99%

Prevalence of antibodies to herpes simplex virus types 1 and 2 in pregnant women, and estimated rates of infection.

Ades

Peckham

Dale

et al. 1989

Journal of Epidemiology & Community Health

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ABSTRACr There has been a recent increase in notifications of genital herpes but it is not known whether this has been reflected in the pregnant population. We have therefore carried out a study to determine the prevalence of herpes simplex antibodies in pregnant women and to estimate the incidence of primary infection. Sera were collected from 3533 women at antenatal clinics and tested for total antibodies to herpes simples virus (HSV), and if positive, for specific antibodies to HSV-2. Estimates of HSV-1 seroprevalence were derived from the HSV-2 seronegative population. HSV-l seroprevalence was nearly 100% in black women born in Africa or the Caribbean and 60-80% in white, Asian and UK born black women. It was lower in women in non-manual employment. HSV-2 seroprevalence was related to age, rising from 0 at age 16 to 40% at age 35 in black women, and to about 10% in Asian and white women. The estimated incidence of primary HSV-2 infection during pregnancy, per 1000 pregnancies, was about 2-4 in Asian women, 5 in white women, and 20 in black women. Estimates of the incidence of neonatal infection were derived from these figures and compared to the nationally reported rates.

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Section: Methodsmentioning

confidence: 99%

Prevalence of antibodies to herpes simplex virus types 1 and 2 in pregnant women, and estimated rates of infection.

Ades

Peckham

Dale

et al. 1989

Journal of Epidemiology & Community Health

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“…'`Most of these patients have severe first episode genital herpes, but the proportion attending again with recurrent infection has increased significantly. 4 Although primary attacks last longer and are more severe than recurrences,5 it is the recurrent nature of the condition that is responsible for the anxiety and psychosexual dysfunction often seen in these patients. 67 Despite many reports on genital herpes, only a handful of studies have looked at the clinical features, viral isolation, and likelihood of transmission in patients with recurrent infection,5 512 and only small numbers ofpatients were studied in all but one ofthese studies.…”

mentioning

confidence: 99%

Recurrent genital herpes: clinical and virological features in men and women.

Mindel

Coker²,

Faherty³

et al. 1988

Sexually Transmitted Infections

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One hundred and forty eight patients (69 women and 79 men) with often recurring genital herpes were observed for two months. Men had 119 observed recurrences and women 104. The attacks were significantly longer in men than women (8.7 days v 6.6 days, p = 0.005). Significantly more women complained of symptoms, however, and when symptoms occurred they were more severe. Other significant differences between men and women included age (men were older than women); more men had previously had sexually transmitted diseases; more men had infected a sexual partner, but fewer knew the source of their infection; and men had more lesions at each attack. Positive viral culture results were shown to depend on the amount of erythema, the number of lesions, and the presence of vesicles.

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“…Herpes had always been with us, but was less prevalent, or not serious enough to attract the venereologist’s attention 23. Heightened interest in the late '70s24 probably reflects rising prevalence 25. Effective treatment emerges with Acyclovir, first reported in 1983 26…”

Section: –1990: the Rise Of The ‘Viruses’mentioning

confidence: 99%

One hundred years of STIs: the expansion of venereal medicine through the pages of its journal

Goode

2017

Sex Transm Infect

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Genital herpes: an increasing problem?

Cited by 8 publications

References 5 publications

Prevalence of antibodies to herpes simplex virus types 1 and 2 in pregnant women, and estimated rates of infection.

Prevalence of antibodies to herpes simplex virus types 1 and 2 in pregnant women, and estimated rates of infection.

Recurrent genital herpes: clinical and virological features in men and women.

One hundred years of STIs: the expansion of venereal medicine through the pages of its journal

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