Genital human papillomaviruses among women of reproductive age in Jamaica

Lewis-Bell, Karen; Luciani, Silvana; Unger, Elizabeth R.; Hariri, Susan; McFarlane, Shelly R.; Steinau, Martin; Prieto-Lara, Elisa; Vicari, Andrea; Irons, Beryl; Lewis, Merle; Andrus, Jon Kim

doi:10.1590/s1020-49892013000300001

Cited by 18 publications

(18 citation statements)

References 10 publications

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“…Infectious diseases, particularly sexually transmitted infections (Snead et al, 2017; Lewis-Bell et al, 2013) and vector-borne diseases (Brown, Vickers, Salas, & Smikle, 2009; Wood et al, 2014), are of concern in the Jamaican population. For example, studies have reported 100% seroprevalence of dengue virus antibodies in the general population (Brown et al, 2009) and among pregnant women (Wood et al, 2014) in Jamaica.…”

Section: Introductionmentioning

confidence: 99%

Maternal Exposures Associated with Autism Spectrum Disorder in Jamaican Children

Christian

Samms‐Vaughan

Lee

et al. 2018

J Autism Dev Disord

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Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder with poorly understood etiology. Many maternal exposures during pregnancy and breastfeeding potentially interfere with neurodevelopment. Using data from two age- and sex-matched case-control studies in Jamaica (n = 298 pairs), results of conditional logistic regression analyses suggest that maternal exposures to fever or infection (matched odds ratio (MOR) = 3.12, 95% CI 1.74-5.60), physical trauma (MOR 2.02, 95% CI 1.01-4.05), and oil-based paints (MOR 1.99, 95% CI 1.14-3.46) may be associated with ASD. Additionally, maternal exposure to oil-based paints may modify the relationship between maternal exposure to pesticides and ASD, which deepens our understanding of the association between pesticides and ASD.

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Section: Introductionmentioning

confidence: 99%

Maternal Exposures Associated with Autism Spectrum Disorder in Jamaican Children

Christian

Samms‐Vaughan

Lee

et al. 2018

J Autism Dev Disord

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“…Although cervical cancer screening services are available and provided at no cost to all nationals of TT, the only data currently available have estimated that Papanicolaou (Pap and/or cytological testing) is utilized for cervical cancer screening at substantially low rates (18.4–35.4%) [8, 20, 21], and almost 50% of those sampled reported having never been screened [8]. It is also worth noting that currently in TT, although annual screening is suggested for all sexually active women (no specified age at first screen), there is no specific national cervical cancer screening program in place [20].…”

Section: Discussionmentioning

confidence: 99%

“…Our recent analysis of TT cancer surveillance data (unpublished data) showed that the cervical cancer mortality rate in TT was 9.7 per 100,000. Few studies have examined the risk factors for cervical cancer mortality in Caribbean populations and have suggested that some of the most important risk factors include: older age at diagnosis [4], tumor clinicopathologic features that are indicative of poor prognosis [4], geographical and sociodemographic factors [4, 5], reduced access to effective treatment [3, 6, 7], reduced access to human papillomavirus (HPV) vaccination [3–5, 8], and reduced access to cervical cancer screening and early detection [3–5, 7–9]. In developing countries, as cervical cancer screening rates have increased over the past few decades, cervical cancer incidence rates have significantly declined, but the decline has been modest throughout the Caribbean.…”

Section: Introductionmentioning

confidence: 99%

Gynecologic cancer mortality in Trinidad and Tobago and comparisons of mortality-to-incidence rate ratios across global regions

Llanos

Warner

Luciani

et al. 2017

Cancer Causes Control

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Purpose To examine the factors associated with gynecologic cancer mortality risks, to estimate the mortality-to-incidence rate ratios (MIR) in Trinidad and Tobago (TT), and to compare the MIRs to those of select countries. Methods Data on 3,915 incident gynecologic cancers reported to the National Cancer Registry of TT from 1 January 1995 to 31 December 2009 were analyzed using proportional hazards models to determine factors associated with mortality. MIRs for cervical, endometrial, and ovarian cancers were calculated using cancer registry data (TT), GLOBOCAN 2012 incidence data, and WHO Mortality Database 2012 data (WHO regions and select countries). Results Among the 3,915 incident gynecologic cancers diagnosed in TT during the study period, 1,795 (45.8%) were cervical, 1,259 (32.2%) were endometrial, and 861 (22.0%) were ovarian cancers. Older age, African ancestry, geographic residence, tumor stage, and treatment non-receipt were associated with increased gynecologic cancer mortality in TT. Compared to GLOBOCAN 2012 data, TT MIR estimates for cervical (0.49 vs. 0.53), endometrial (0.61 vs. 0.65), and ovarian cancers (0.32 vs. 0.48) were elevated. While the Caribbean region had intermediate gynecologic cancer MIRs, MIRs in TT were among the highest of the countries examined in the Caribbean region. Conclusions Given its status as a high-income economy, the relatively high gynecologic cancer MIRs observed in TT are striking. These findings highlight the urgent need for improved cancer surveillance, screening, and treatment for these (and other) cancers in this Caribbean nation.

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“…However, studies that have assessed oral HPV in HIV‐positive individuals have been largely inconsistent, reporting a prevalence of 2.1%‐39% . Genital HPV prevalence studies have been undertaken to demonstrate type and distribution in the Caribbean, and in Jamaica, the genital HPV prevalence reported was at 54% and oncogenic HPV prevalence was 34.9% . However, no studies have been reported in regard to oral HPV prevalence in Jamaica or other Caribbean countries.…”

Section: Introductionmentioning

confidence: 99%

Molecular epidemiology of human papillomavirus genotypes in oral rinses from HIV‐positive and HIV‐negative Jamaican patients

Santosh

Christian

Jones

et al. 2018

J of Invest & Clin Dent

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Aim Human papillomavirus (HPV) has been reported to be associated with oral and oropharyngeal cancer. However, little information is available about the epidemiology of oral HPV infection in Jamaica. The purpose of the present study was to assess the prevalence of oral HPV strains using the oral rinse method in HIV and non‐HIV Jamaican patients, as well as to determine the association of HPV with sexual practices, smoking, and alcohol use. Methods A cross‐sectional study was conducted on patients attending The University of the West Indies Mona Dental Polyclinic and the Centre for HIV/AIDS Research and Education Services. Salivary samples were tested through molecular analysis for 37 HPV genotypes using the linear array HPV genotyping test. A survey questionnaire was used to obtain demographic details, smoking history, alcohol practice, sexual practice, and history of HPV testing. Results The HPV prevalence was 8.65% in 18‐64 y olds (N = 104), with a slight female predilection (55%). No high‐risk HPV types were found. HPV‐84 was the most common type in both HIV and non‐HIV patients; 66.7% of HPV‐positive participants reported that they had six or more lifetime sexual partners. Conclusion The prevalence of oral HPV was similar to that in other countries. No statistically‐significant relationship was observed between the prevalence of HPV and either the number of sexual partners, smoking, or alcohol history. A nationwide study on oral HPV detection might be helpful in developing a HPV vaccination policy in Jamaica.

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Genital human papillomaviruses among women of reproductive age in Jamaica

Cited by 18 publications

References 10 publications

Maternal Exposures Associated with Autism Spectrum Disorder in Jamaican Children

Maternal Exposures Associated with Autism Spectrum Disorder in Jamaican Children

Gynecologic cancer mortality in Trinidad and Tobago and comparisons of mortality-to-incidence rate ratios across global regions

Molecular epidemiology of human papillomavirus genotypes in oral rinses from HIV‐positive and HIV‐negative Jamaican patients

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