Genital mycoplasma infection and spontaneous preterm birth outcome: a prospective cohort study

Modeling ascending Ureaplasma parvum infection through the female reproductive tract using vagina‐cervix‐decidua‐organ‐on‐a‐chip and feto‐maternal interface‐organ‐on‐a‐chip

“…This shows that, if cervical cells maintain their functional roles (mimicking an intact cervix), U. parvum alone cannot promote the inflammation needed to induce PTB unless it reaches the amniotic cavity or other more pathogenic organisms, such as E. coli , are present in the cervicovaginal canal. These findings (in vitro OOC model results predictive of in vivo animal model results) are in line with what we have postulated previously based on an in vitro organ explant model of fetal membranes and clinical data showing the lack of association between genital mycoplasma and PTB 58,59 . In that previous study, we reported that Ureaplasma spp.…”

Re: Obstetric anal sphincter injury by maternal origin and length of residence

“…A subgroup analysis comparing the newborn birthweight and head circumference could be instrumental in solving this dilemma. Previous studies by Vik et al 2 from Norway had demonstrated similar outcomes in neonatal survival as well. In the absence of a significant difference in newborn birthweight and head circumference, social issues need due consideration.…”

“…1 First, we would like to comment on the nature of the population selected for our study. 2 Due to the registry-based study design of our study, we depend on the classifications from the Population Registry. Thus, the category of foreign-born women with Norwegian-born parents is a case-mix consisting of adoptees as well as children born to Norwegian couples coincidentally living abroad at the time of the birth.…”