Genitourinary tract infection in children due to Aerococcus other than Aerococcus viridans. Literature review and 3 case reports

Gutiérrez‐Fernández, José; Gámiz-Gámiz, Antonio; Navarro-Marí, José María; Santos-Pérez, Juan Luis

doi:10.1016/j.eimce.2020.05.008

Cited by 3 publications

(4 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…and SBG can be confused with enterococci and streptococci due to their phenotypic similarities, and the detection of Corynebacterium spp. may be limited by their growth characteristics and need for enriched media [8]. It is important to consider factors that may increase the risk of infection by these agents, including the presence of anatomical urinary tract or prostate disorders, diabetes mellitus, permanent vesical catheter, solid organ transplantation, pharmacological immunosuppression, or recent antibiotic consumption (in previous 3 months) [12].…”

Section: Discussionmentioning

confidence: 99%

“…However, other pathogens are emerging as responsible for these diseases in certain clinical settings. These microorganisms may have been overlooked or poorly classified due to the lack of distinctive phenotypic criteria, the consideration of their significant growth as contamination by microbiota, and failure in their detection by standard methods, sometimes because of their slow growth and the need for nutritionally demanding culture media [8,9]. Advances in microbiological techniques have revealed new scenarios of clinical and microbiological relevance and increased the detection of these pathogens, including Corynebacterium spp., Aerococcus spp., Actinotignum spp., Actinobaculum massiliense, Actinomyces turicensis, Alloscardovia omnicolens, Aeromonas hydrophila, Eikenella corrodens, Lactobacillus spp., Streptococcus bovis group (SBG), pneumoniae, and viridans group (SVG), Leptotrichia trevisanii, Facklamia spp., Pasteurella spp., Neisseria meningitidis, and Gardnerella spp.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Presence and Relevance of Emerging Microorganisms in Clinical Genitourinary Samples

et al. 2023

View full text Add to dashboard Cite

Microorganisms responsible for genitourinary infections increasingly include species other than conventional etiological agents that are of clinical and pathogenic relevance and therapeutic interest. This cross-sectional descriptive study selected samples from clinical genitourinary episodes between January 2016 and December 2019 in which emerging microbiological agents were detected. The patients’ epidemiological characteristics, clinical presentation, antibiotic treatment, and outcome were studied to identify their pathogenic role. The emerging microorganisms most frequently detected in urinary tract infections were Streptococcus bovis (58.5%) and Gardnerella spp. (23.6%) in females and S. bovis (32.3%), Aerococcus urinae (18.6%), and Corynebacterium spp. (16.9%) in males, while the most frequently detected in genital infections were S. viridans (36.4%) in females and C. glucuronolyticum (32.2%) and Gardnerella spp. (35.6%) in males. All cases in female children were produced by S. bovis. Symptomatic episodes were more frequent with Aerococcus spp. and S. bovis and the presence of leukocytosis more frequent with Aerococcus spp. Quinolones and doxycycline were most often prescribed antibiotics for genital infections and quinolones and amoxicillin-clavulanic acid for urinary infections. Urinary infection by Aerococcus spp. was more frequent in males of advanced age, Corynebacterium spp. was more frequent in permanent vesical catheter carriers, and episodes of asymptomatic bacteriuria by Gardnerella spp. were more frequent in patients with kidney transplant and chronic consumers of corticosteroid therapy. Lactobacillus spp. should be considered in urinary infections of patients of advanced age and with a previous antibiotic load. Genital infection by Gardnerella spp. was significantly associated with a history of risky sexual relations.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Presence and Relevance of Emerging Microorganisms in Clinical Genitourinary Samples

et al. 2023

View full text Add to dashboard Cite

show abstract

“…In our study, we isolated 14 bacterial strains from 11 samples collected from six Romanian caves; some of these species could cause human infections. Aerococcus viridian is a rarely reported Gram-positive cocci, opportunistic organism in endocarditis or urinary tract infections [ 86 , 87 ]. Rhodococcus coprophilus is a Gram-positive aerobic bacteria that is a fecal indicator of freshwater [ 88 ].…”

Section: Discussionmentioning

confidence: 99%

The Gram-Negative Bacilli Isolated from Caves—Sphingomonas paucimobilis and Hafnia alvei and a Review of Their Involvement in Human Infections

Ionescu

Neagoe

Crăciun

et al. 2022

IJERPH

View full text Add to dashboard Cite

The opportunistic infections with Gram-negative bacilli are frequently reported. The clinical studies are focused on the course of human infectious and very often the source of infection remain unclear. We aim to see if the Gram-negative bacilli isolated from a non-contaminated environment—the caves—are reported in human infections. Eleven samples were collected from six Romanian caves. We used the standard procedure used in our clinical laboratory for bacterial identification and for antibiotic susceptibility testing of the cave isolates. Out of the 14 bacterial strains, three isolates are Gram-negative bacilli—one isolate belong to Hafnia alvei and two strains belong to Sphingomonas paucimobilis. We screened for the published studies—full-text original articles or review articles—that reported human infections with S. paucimobilis and H. alvei. Data sources—PubMed and Cochrane library. We retrieved 447 cases from 49 references—262 cases (58.61%) are S. paucimobilis infections and 185 cases (41.39%) are H. alvei infections. The types of infections are diverse but there are some infections more frequent; there are 116 cases (44.27%) and many infections of the bloodstream with S. paucimobilius (116 cases) and 121 cases (65.41%) are urinary tract infections with H. alvei. The acquired source of the bloodstream infections is reported for 93 of S. paucimobilis bloodstream infections—50 cases (43%) are hospital-acquired, and 40 cases (37%) are community-acquired. Most of the infections are reported in patients with different underlying conditions. There are 80 cases (17.9%) are reported of previously healthy persons. Out of the 72 cases of pediatric infections, 62 cases (86.11%) are caused by S. paucimobilis. There are ten death casualties—three are H. alvei infections, and seven are S. paucimobilis infections.

show abstract

“…Another relevant genus is Aerococcus spp., highlighting the predominance of A. urinae and A. sanguinicola in elderly males with underlying urological disease, who are at higher risk of UTI from infrequent pathogens [ 28 ]. Nevertheless, its possible presence should also be considered in adolescents because the diagnosis is often delayed and potentially severe disease (e.g., pyelonephritis, bacteremia, endocarditis or peritonitis) can develop [ 29 ]. It is therefore important to rule out the genus Aerococcus genus when a urine culture has a significant alpha-hemolytic microorganism count before reporting it as urogenital microbiota.…”

Section: Discussionmentioning

confidence: 99%

Emerging Presence of Culturable Microorganisms in Clinical Samples of the Genitourinary System: Systematic Review and Experience in Specialized Care of a Regional Hospital

Rosales-Castillo

Jiménez‐Guerra

Ruiz-Gómez

et al. 2022

JCM

Self Cite

View full text Add to dashboard Cite

The detection of emerging pathogens responsible for genitourinary infections has increased with technological advances. We conducted a systematic review of publications on the involvement of these microorganisms in genitourinary samples, and we also investigated their presence and antibiotic susceptibility in samples from patients at our regional hospital (Granada, Spain). The MEDLINE database was searched up to 31 December 2020, and a cross-sectional descriptive study was performed of results obtained in urine samples and genital exudates from January 2016 through December 2019. The review highlighted the frequent involvement of Neisseria meningitidis in genital infections, while the data on other microorganisms were consistent with findings in our patient series. The emerging microorganisms most often responsible for urinary tract infections were Streptococcus bovis (58.5%) and Gardnerella vaginalis (23.6%) in females, and S. bovis (32.3%), Aerococcus urinae (18.6%), and Corynebacterium spp. (16.9%) in males; those most frequently reported in genital infections were S. viridans (36.4%) in females and C. glucuronolyticum (32.2%) and G. vaginalis (35.6%) in males. In general, emerging pathogens are resistant to conventional antibiotics such as penicillin. However, there has also been an increase in beta-lactam resistance by the S. bovis group and Corynebacterium spp. The systematic review showed that emerging microorganisms are responsible for only a small percentage of genitourinary infections but are of major clinical interest, with a predominance of the S. bovis group, G. vaginalis, Lactobacillus spp., Aerococcus spp., and Corynebacterium spp. in urine samples and of G. vaginalis and C. glucuronolyticum in genital samples. Given the increasing resistance to antibiotics empirically prescribed in patients with genitourinary infections, it is recommended to create an antibiogram in all cases.

show abstract

Genitourinary tract infection in children due to Aerococcus other than Aerococcus viridans. Literature review and 3 case reports

Cited by 3 publications

References 9 publications

Presence and Relevance of Emerging Microorganisms in Clinical Genitourinary Samples

Presence and Relevance of Emerging Microorganisms in Clinical Genitourinary Samples

The Gram-Negative Bacilli Isolated from Caves—Sphingomonas paucimobilis and Hafnia alvei and a Review of Their Involvement in Human Infections

Emerging Presence of Culturable Microorganisms in Clinical Samples of the Genitourinary System: Systematic Review and Experience in Specialized Care of a Regional Hospital

Contact Info

Product

Resources

About